Brioni Elena, Magnaghi Cristiano, Villa Giulia, Giannetta Noemi, Manara Duilio F, Magni Giulia, Delli ZOtti Giulia, Fontana Simone, Tunesi Francesca, Zagato Laura, Lanzani Chiara, Manfredi Angelo, Manunta Paolo
IRCCS Ospedale San Raffaele, Milano, Italia.
Centro per la ricerca e innovazione infermieristica, Università Vita Salute San Raffaele, Milano, Italia.
G Ital Nefrol. 2022 Jun 20;39(3):2022-vol3.
Chronic renal failure is an epidemic in elderly patients. Older population have an increased prevalence of frailty and sarcopenia, associated with a wide range of adverse health outcomes such as falls, hospitalization, disability. Describe the sociodemographic and clinical variables of an elderly Lombard population and identify predictors of renal insufficiency. Cross-sectional observational study conducted in hospitals, in recreational centers for the elderly, in the Universities of the Third Age of the provinces of Milan and Monza-Brianza conducted through a convenience sampling of 1250 subjects over the age of 65. The study identified living alone, annual individual income < € 10,000, polypharmacy, sarcopenia and frailty as predictors of chronic kidney failure. The sample has a mean eGFR of 71.74 mL/min/1.73m2 (SD ± 16.56). Older people living alone are more likely to develop CRI (P = 0.031, confidence interval, CI [1.031-1.905]) as well as having an income < € 10,000 (P = 0.002, CI [0.392-0.923]). Taking more than 11 drugs a day increases the probability of having chronic renal failure by 16 times (P = 0.012, CI [1.155-3.16]). Sarcopenia and frailty increase the likelihood of having chronic renal failure (CRI) (P = 0.001, CI [1.198-2.095]). Identifying predictors of chronic kidney failure is a key step in introducing preventive measures and providing better care to the elderly population.
慢性肾衰竭在老年患者中呈流行趋势。老年人群体中虚弱和肌肉减少症的患病率增加,这与跌倒、住院、残疾等一系列不良健康后果相关。描述伦巴第老年人群体的社会人口统计学和临床变量,并确定肾功能不全的预测因素。通过对米兰省和蒙扎 - 布里安扎省1250名65岁以上受试者进行便利抽样,在医院、老年娱乐中心、第三年龄大学开展横断面观察性研究。该研究确定独居、个人年收入低于10000欧元、多重用药、肌肉减少症和虚弱是慢性肾衰竭的预测因素。样本的平均估算肾小球滤过率(eGFR)为71.74 mL/min/1.73m²(标准差±16.56)。独居的老年人更有可能发生慢性肾衰竭(P = 0.031,置信区间,CI [1.031 - 1.905]),年收入低于10000欧元的情况也是如此(P = 0.002,CI [0.392 - 0.923])。每天服用超过11种药物会使患慢性肾衰竭的概率增加16倍(P = 0.012,CI [1.155 - 3.16])。肌肉减少症和虚弱会增加患慢性肾衰竭(CRI)的可能性(P = 0.001,CI [1.198 - 2.095])。确定慢性肾衰竭的预测因素是采取预防措施和为老年人群提供更好护理的关键一步。