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多模态运动辅助记忆脱敏与再巩固硬件和软件的重新设计与验证:混合方法、基于德尔菲法改进的验证研究

The Redesign and Validation of Multimodal Motion-Assisted Memory Desensitization and Reconsolidation Hardware and Software: Mixed Methods, Modified Delphi-Based Validation Study.

作者信息

Jones Chelsea, Smith-MacDonald Lorraine, Brown Matthew R G, VanDehy Jacob, Grunnet-Jepsen Rasmus, Ordek Vrajeshri P, Kruger Sarah, Ayres Gerhart Anne, van Veelen Nancy, Nijdam Mirjam J, Burback Lisa, Cao Bo, Roy Michael J, Sessoms Pinata, Vermetten Eric, Brémault-Phillips Suzette

机构信息

Leiden University Medical Center, Leiden University, Leiden, Netherlands.

Heroes in Mind, Advocacy and Research Consortium, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.

出版信息

JMIR Hum Factors. 2022 Jul 12;9(3):e33682. doi: 10.2196/33682.

Abstract

BACKGROUND

In recent years, the delivery of evidence-based therapies targeting posttraumatic stress disorder (PTSD) has been the focus of the Departments of Defense in countries such as Canada, the Netherlands, and the United States. More than 66% of military members continue to experience symptoms of PTSD that significantly impact their daily functioning and quality of life after completing evidence-based treatments. Innovative, engaging, and effective treatments for PTSD are needed. Multimodal motion-assisted memory desensitization and reconsolidation (3MDR) is an exposure-based, virtual reality-supported therapy used to treat military members and veterans with treatment-resistant PTSD. Given the demonstrated efficacy of 3MDR in recently published randomized control trials, there is both an interest in and a need to adapt the intervention to other populations affected by trauma and to improve accessibility to the treatment.

OBJECTIVE

We aimed to further innovate, develop, and validate new and existing hardware and software components of 3MDR to enhance its mobility, accessibility, feasibility, and applicability to other populations affected by trauma, including public safety personnel (PSP), via international collaboration.

METHODS

This study used a modified Delphi expert consultation method and mixed methods quasi-experimental validation with the purpose of software validation among PSP (first responders, health care providers) participants (N=35). A team of international experts from the Netherlands, the United States, and Canada met on the web on a weekly basis since September 2020 to discuss the adoption of 3MDR in real-world contexts, hardware and software development, and software validation. The evolution of 3MDR hardware and software was undertaken followed by a mixed methods software validation study with triangulation of results to inform the further development of 3MDR.

RESULTS

This study resulted in the identification, description, and evolution of hardware and software components and the development of new 3MDR software. Within the software validation, PSP participants widely acknowledged that the newly developed 3MDR software would be applicable and feasible for PSP affected by trauma within their professions. The key themes that emerged from the thematic analysis among the PSP included the desire for occupationally tailored environments, individually tailored immersion, and the applicability of 3MDR beyond military populations.

CONCLUSIONS

Within the modified Delphi consultation and software validation study, support for 3MDR as an intervention was communicated. PSP participants perceived that 3MDR was relevant for populations affected by trauma beyond military members and veterans. The resulting hardware and software evolution addressed the recommendations and themes that arose from PSP participants. 3MDR is a novel, structured, exposure-based, virtual reality-supported therapy that is currently used to treat military members and veterans with PTSD. Going forward, it is necessary to innovate and adapt 3MDR, as well as other trauma interventions, to increase effectiveness, accessibility, cost-effectiveness, and efficacy among other populations affected by trauma.

摘要

背景

近年来,在加拿大、荷兰和美国等国家,提供针对创伤后应激障碍(PTSD)的循证疗法一直是国防部关注的焦点。超过66%的军人在完成循证治疗后,仍持续出现PTSD症状,这对他们的日常功能和生活质量产生了重大影响。因此,需要创新、引人入胜且有效的PTSD治疗方法。多模式运动辅助记忆脱敏与再巩固疗法(3MDR)是一种基于暴露、虚拟现实支持的疗法,用于治疗患有难治性PTSD的军人和退伍军人。鉴于3MDR在最近发表的随机对照试验中已证明其有效性,人们既对将该干预措施应用于其他受创伤人群感兴趣,也有这样的需求,同时还需要提高该治疗方法的可及性。

目的

我们旨在通过国际合作,进一步创新、开发和验证3MDR的新硬件和软件组件,以增强其移动性、可及性、可行性以及对包括公共安全人员(PSP)在内的其他受创伤人群的适用性。

方法

本研究采用了改良的德尔菲专家咨询法和混合方法准实验验证,目的是在PSP(急救人员、医疗保健提供者)参与者(N = 35)中进行软件验证。自2020年9月以来,来自荷兰、美国和加拿大的国际专家团队每周在网上开会,讨论3MDR在实际应用中的采用情况、硬件和软件开发以及软件验证。在进行3MDR硬件和软件的改进之后,开展了一项混合方法软件验证研究,并对结果进行三角测量,以为3MDR的进一步开发提供参考。

结果

本研究确定、描述并改进了硬件和软件组件,并开发了新的3MDR软件。在软件验证过程中,PSP参与者广泛认可新开发的3MDR软件对其职业中受创伤的PSP是适用且可行的。PSP主题分析中出现的关键主题包括对适合职业环境的需求、个性化的沉浸体验以及3MDR在军人以外人群中的适用性。

结论

在改良的德尔菲咨询和软件验证研究中,传达了对3MDR作为一种干预措施的支持。PSP参与者认为3MDR与军人和退伍军人以外的受创伤人群相关。由此产生的硬件和软件改进解决了PSP参与者提出的建议和主题。3MDR是一种新颖的、结构化的、基于暴露的、虚拟现实支持的疗法,目前用于治疗患有PTSD的军人和退伍军人。展望未来,有必要对3MDR以及其他创伤干预措施进行创新和调整,以提高其在其他受创伤人群中的有效性、可及性、成本效益和疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffb6/9328788/9c34ecd91ff5/humanfactors_v9i3e33682_fig1.jpg

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