Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor.
Department of Heart and Vascular Services, Beaumont Hospital, Royal Oak, Michigan.
JAMA Netw Open. 2022 Jul 1;5(7):e2222089. doi: 10.1001/jamanetworkopen.2022.22089.
This cohort study evaluates stroke and major bleeding rates before and after switching from warfarin to a direct oral anticoagulant (DOAC) in patients grouped by pre-switch time-in-therapeutic range guideline thresholds.
本队列研究评估了在根据预切换时治疗范围指南阈值分组的患者中,从华法林切换为直接口服抗凝剂(DOAC)前后的卒中发生率和大出血发生率。