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膳食类黄酮摄入量与慢性感觉障碍:一项范围综述

Dietary Flavonoid Intake and Chronic Sensory Conditions: A Scoping Review.

作者信息

Tang Diana, Tran Yvonne, Shekhawat Giriraj S, Gopinath Bamini

机构信息

Macquarie University Hearing, Faculty of Medicine Health and Human Sciences, Macquarie University, Sydney, NSW 2109, Australia.

College of Nursing and Health Sciences, Flinders University, Adelaide, SA 5001, Australia.

出版信息

Antioxidants (Basel). 2022 Jun 21;11(7):1214. doi: 10.3390/antiox11071214.

Abstract

Dietary flavonoids have antioxidant, anti-inflammatory, and vascular health benefits, which align with the proposed pathophysiology of age-related eye conditions and hearing problems (hearing loss and tinnitus). This scoping review is based on Arksey and O'Malley's six-stage framework and aims to summarise current evidence on the association between the dietary flavonoid intake and chronic sensory conditions in adults, and to identify the research gaps in this area. Eligible studies were identified by searching MEDLINE, EMBASE PsycINFO via the OVID platform, and Google Scholar, as well as manually searching the reference lists of the eligible articles. The inclusion criteria included: articles with full-text access, written in the English language, and focused on chronic sensory conditions and dietary flavonoid intake in an adult population. Studies focused on flavonoid supplements were excluded. Ten studies were included in this review. The evidence suggests that the flavonoid subclass, flavonols, are protective against eye conditions, including age-related macular degeneration, cataract, and glaucoma. There is insufficient evidence to support an association with hearing loss or tinnitus. Overall, dietary flavonol intake appears to be protective against some chronic eye conditions. However, for most eye and hearing-related conditions, only one study was identified. Thus, there is a need for more recent high-quality research to be conducted to confirm any significant associations.

摘要

膳食类黄酮具有抗氧化、抗炎和有益血管健康的作用,这与年龄相关性眼部疾病和听力问题(听力损失和耳鸣)的病理生理学机制相符。本综述基于阿克西和奥马利的六阶段框架,旨在总结目前关于成人膳食类黄酮摄入量与慢性感觉障碍之间关联的证据,并找出该领域的研究空白。通过在OVID平台上检索MEDLINE、EMBASE、PsycINFO以及谷歌学术来识别符合条件的研究,同时人工检索符合条件文章的参考文献列表。纳入标准包括:可获取全文、用英语撰写且聚焦于成人慢性感觉障碍和膳食类黄酮摄入量的文章。聚焦于类黄酮补充剂的研究被排除。本综述纳入了10项研究。证据表明,类黄酮亚类黄酮醇对眼部疾病具有保护作用,包括年龄相关性黄斑变性、白内障和青光眼。没有足够的证据支持其与听力损失或耳鸣有关联。总体而言,膳食中黄酮醇的摄入似乎对某些慢性眼部疾病具有保护作用。然而,对于大多数与眼睛和听力相关的疾病,仅识别出一项研究。因此,需要开展更多最新的高质量研究来证实是否存在任何显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9287/9311508/ce5a2ecf71e3/antioxidants-11-01214-g001.jpg

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