Ferroptosis vulnerability in MYCN-driven neuroblastomas.
作者信息
Dasgupta Shayani, Gan Boyi
机构信息
Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas, USA.
出版信息
Clin Transl Med. 2022 Aug;12(8):e963. doi: 10.1002/ctm2.963.
Abstract
摘要
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本文引用的文献
1
MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Nat Cancer. 2022 Apr;3(4):471-485. doi: 10.1038/s43018-022-00355-4. Epub 2022 Apr 28.
2
Targeting ferroptosis as a vulnerability in cancer.
Nat Rev Cancer. 2022 Jul;22(7):381-396. doi: 10.1038/s41568-022-00459-0. Epub 2022 Mar 25.
3
Ferroptosis: mechanisms, biology and role in disease.
Nat Rev Mol Cell Biol. 2021 Apr;22(4):266-282. doi: 10.1038/s41580-020-00324-8. Epub 2021 Jan 25.
4
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy.
Protein Cell. 2021 Aug;12(8):599-620. doi: 10.1007/s13238-020-00789-5. Epub 2020 Oct 1.
5
Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation.
Cell Metab. 2019 Nov 5;30(5):865-876.e5. doi: 10.1016/j.cmet.2019.09.009. Epub 2019 Oct 10.
6
Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer.
Cancer Commun (Lond). 2018 Apr 25;38(1):12. doi: 10.1186/s40880-018-0288-x.
7
MYC, Metabolism, and Cancer.
Cancer Discov. 2015 Oct;5(10):1024-39. doi: 10.1158/2159-8290.CD-15-0507. Epub 2015 Sep 17.
8
Ferroptosis: an iron-dependent form of nonapoptotic cell death.
Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042.
9
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Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
10
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