Khader Ali, Braschi-Amirfarzan Marta, McIntosh Lacey J, Gosangi Babina, Wortman Jeremy R, Wald Christoph, Thomas Richard
Department of Radiology, Lahey Hospital and Medical Center, Tufts University School of Medicine, 41 Mall Road, Burlington, MA 01805, the United States of America.
University of Massachusetts Chan Medical School/Memorial Health Care, Division of Oncologic and Molecular Imaging, 55 Lake Avenue North, Worcester, MA 01655, the United States of America.
Eur J Radiol Open. 2022 Jul 26;9:100433. doi: 10.1016/j.ejro.2022.100433. eCollection 2022.
Cancer therapy has evolved from being broadly directed towards tumor types, to highly specific treatment protocols that target individual molecular subtypes of tumors. With the ever-increasing data on imaging characteristics of tumor subtypes and advancements in imaging techniques, it is now often possible for radiologists to differentiate tumor subtypes on imaging. Armed with this knowledge, radiologists may be able to provide specific information that can obviate the need for invasive methods to identify tumor subtypes. Different tumor subtypes also differ in their patterns of metastatic spread. Awareness of these differences can direct radiologists to relevant anatomical sites to screen for early metastases that may otherwise be difficult to detect during cursory inspection. Likewise, this knowledge will help radiologists to interpret indeterminate findings in a more specific manner.
癌症治疗已从广泛针对肿瘤类型，发展到针对肿瘤个体分子亚型的高度特异性治疗方案。随着关于肿瘤亚型成像特征的数据不断增加以及成像技术的进步，放射科医生现在通常能够在成像上区分肿瘤亚型。有了这些知识，放射科医生或许能够提供特定信息，从而无需采用侵入性方法来识别肿瘤亚型。不同的肿瘤亚型在转移扩散模式上也存在差异。了解这些差异可以引导放射科医生前往相关解剖部位筛查早期转移灶，否则这些转移灶在粗略检查时可能难以发现。同样，这些知识将帮助放射科医生更具体地解读不确定的检查结果。
