Mercers Institute for Research on Ageing, St James's Hospital, Dublin 8, Ireland.
School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
J Nutr Sci. 2022 Jul 25;11:e61. doi: 10.1017/jns.2022.57. eCollection 2022.
Vitamin D is essential for bone and muscle health with adequate status in childhood crucial for normal skeletal development. We aimed to investigate vitamin D status in a convenience sample ( = 1226) of Irish children (aged 1-17 years) who had serum 25-hydroxyvitamin D (25(OH)D) tested by request of their GP at a Dublin Hospital between 2014 and 2020. We examined predictors including age, sex, season and socioeconomic status (SES). Vitamin D deficiency (<30 nmol/l) was prevalent affecting 23 % and was more common in disadvantaged areas (34 %) and in those aged >12 . ≤12 years (24 % . 16 %, = 0⋅033). The greatest predictor was SES (disadvantaged . affluent, OR 2⋅18, CI 1⋅34, 3⋅53, = 0⋅002), followed by female sex (OR 1⋅57, CI 1⋅15, 2⋅14, = 0⋅005) and winter season (October to February, OR 1⋅40, CI 1⋅07, 1⋅84, = 0⋅015). A quarter of our sample of children were deficient, rising to one-third in those in disadvantaged areas. Females and those aged over 12 years had a higher prevalence of deficiency. Public health strategies to improve vitamin D status in Irish children, including systematic food fortification may need to be considered to address this issue.
维生素 D 对骨骼和肌肉健康至关重要,儿童时期有足够的维生素 D 状态对正常骨骼发育至关重要。我们旨在调查 2014 年至 2020 年间,都柏林医院的全科医生应患者要求对 1226 名爱尔兰儿童(年龄在 1-17 岁之间)的血清 25-羟维生素 D(25(OH)D)进行检测,以了解他们的维生素 D 状态。我们检查了包括年龄、性别、季节和社会经济地位(SES)在内的预测因素。维生素 D 缺乏症(<30nmol/l)的患病率为 23%,在贫困地区(34%)和年龄大于 12 岁的人群中更为常见(24%和 16%,=0.033)。最大的预测因素是 SES(贫困与富裕,OR2.18,CI1.34,2.53,=0.002),其次是女性(OR1.57,CI1.15,2.14,=0.005)和冬季(10 月至 2 月,OR1.40,CI1.07,1.84,=0.015)。我们样本中四分之一的儿童缺乏维生素 D,在贫困地区这一比例上升到三分之一。女性和年龄超过 12 岁的儿童维生素 D 缺乏症的患病率更高。为了解决这个问题,可能需要考虑在爱尔兰儿童中实施改善维生素 D 状态的公共卫生策略,包括系统的食物强化。