Pediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University Hospital, P.O Box 80205, Jeddah, 21589, Saudi Arabia.
Pediatric Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
Qual Life Res. 2022 Dec;31(12):3413-3421. doi: 10.1007/s11136-022-03179-y. Epub 2022 Aug 2.
There is limited knowledge about oral health-related quality of life (OHRQoL) in children with celiac disease (CD). This study aimed to assess OHRQoL in children with CD compared to healthy controls.
This case-control study included children with CD and healthy controls. Three scales were used to assess OHRQoL in different age groups: 6-7 years, 8-10 years, and 11-14 years. The OHRQoL scores were compared between cases and controls to examine the possible associations between OHRQoL and demographics, socioeconomic status, and oral health.
Overall, 104 children with CD and 104 healthy children (controls) were included. The mean age was 10.67 ± 2.39 years in CD patients and 10.69 ± 2.36 in controls (P = 0.971). Male and female children constituted 50% of each group. Children with CD had significantly higher OHRQoL scores than controls (P = 0.003). Low education levels of parents of children with CD and a higher number of siblings in controls were associated with high OHRQoL scores (P = 0.002, P < 0.020, and P = 0.010, respectively). Recurrent aphthous stomatitis (RAS) increased the OHRQoL scores by 7.5 on average (P = 0.016).
Children with CD had poor OHRQoL compared with healthy controls. Poor OHRQoL in children with CD was associated with RAS and with lower parental income and education. RAS was an independent predictor of poor OHRQoL in children with CD.
关于乳糜泻(CD)儿童的口腔健康相关生活质量(OHRQoL)知之甚少。本研究旨在评估 CD 患儿与健康对照组的 OHRQoL。
本病例对照研究纳入 CD 患儿和健康对照组。使用三个量表在不同年龄组(6-7 岁、8-10 岁和 11-14 岁)评估 OHRQoL。比较病例和对照组的 OHRQoL 评分,以检查 OHRQoL 与人口统计学、社会经济状况和口腔健康之间的可能关联。
共纳入 104 例 CD 患儿和 104 例健康儿童(对照组)。CD 患儿的平均年龄为 10.67 ± 2.39 岁,对照组为 10.69 ± 2.36 岁(P = 0.971)。男童和女童各占每组的 50%。CD 患儿的 OHRQoL 评分明显高于对照组(P = 0.003)。CD 患儿父母的受教育程度较低,对照组的兄弟姐妹较多,与较高的 OHRQoL 评分相关(P = 0.002、P < 0.020 和 P = 0.010)。复发性阿弗他溃疡(RAS)使 OHRQoL 评分平均增加 7.5 分(P = 0.016)。
与健康对照组相比,CD 患儿的 OHRQoL 较差。CD 患儿的 OHRQoL 较差与 RAS 以及父母收入和教育程度较低有关。RAS 是 CD 患儿 OHRQoL 较差的独立预测因素。