喉浆细胞增多症对布地奈德吸入剂的反应。

Laryngeal Plasmacytosis Responsive to Inhaled Budesonide.

机构信息

Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

出版信息

Laryngoscope. 2023 Jan;133(1):70-72. doi: 10.1002/lary.30328. Epub 2022 Aug 8.

DOI:10.1002/lary.30328

PMID:35938690

Abstract

Mucous membrane plasmacytosis (MMP) is rare condition characterized by diffuse plasma cell infiltration of upper aero-digestive tract mucosa. It results in epithelial hyperplasia that has a classic papillary appearance. We describe a case of MMP primarily affect laryngeal and oropharyngeal mucosa resulting in progressive airway obstruction. We highlight airway management and histopathology. The patient had near complete clinical response with inhaled budesonide, which has not yet been described as a treatment option in the literature. Laryngoscope, 133:70-72, 2023.

摘要

黏膜浆细胞增多症（MMP）是一种罕见的疾病，其特征为上呼吸道-消化道黏膜的弥漫性浆细胞浸润。它导致上皮过度增生，具有典型的乳头状外观。我们描述了一例主要影响喉和口咽黏膜的 MMP 病例，导致进行性气道阻塞。我们强调了气道管理和组织病理学。患者对吸入布地奈德有近乎完全的临床反应，而这在文献中尚未被描述为一种治疗选择。《喉镜》，133：70-72，2023。