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碰撞性肺肿瘤,将典型类癌与硬化性血管瘤相关联。

Collision lung tumor associating typical carcinoid tumor to sclerosing hemangioma.

作者信息

Mlika Mona, Rais Abir, Abdelkbir Amina, Saad Soumeya Ben, Abdennadher Mahdi, Baccouche Ines, El Mezni Faouzi

机构信息

Department of Pathology Abderrahman Mami Hospital Ariana Tunisia.

Laboratory Research: LR18SP06 Tunis Tunisia.

出版信息

Clin Case Rep. 2022 Aug 9;10(8):e6237. doi: 10.1002/ccr3.6237. eCollection 2022 Aug.

Abstract

Collision tumors associating carcinoid tumor and sclerosing pneumocytoma have rarely been reported in the literature. The clinical presentation may be challenging especially in cases showing multiple and bilateral nodules. This case illustrates the association of both tumors diagnosed incidentally and illustrates a full spectrum of neuroendocrine lesions and sclerosing pneumocytoma. The authors present the case of a 52-year-old patient presenting an abdominal pain revealing a vesicular lithiasis and multiple pulmonary nodules. Radiologic follow-up of the asymptomatic lung lesions revealed the stabilization of a left lobe lesion with a disappearance of the other lesions. A lobectomy with a mediastinal lymph node curettage was performed. The microscopic examination revealed both tumor components associating a typical carcinoid tumor to a sclerosing pneumocytoma in association to lesions of diffuse neuroendocrine hyperplasia present in the peri-tumoral parenchyma. This case illustrates radiologic, gross, and microscopic features of a rare pulmonary tumor.

摘要

类癌肿瘤与硬化性肺细胞瘤相关的碰撞瘤在文献中鲜有报道。临床表现可能具有挑战性,尤其是在出现多发双侧结节的病例中。本病例说明了这两种肿瘤偶然被诊断出的关联,并展示了一系列神经内分泌病变和硬化性肺细胞瘤。作者介绍了一名52岁患者的病例,该患者因腹痛就诊,发现有膀胱结石和多个肺结节。对无症状肺部病变的放射学随访显示,左叶病变稳定,其他病变消失。进行了肺叶切除术及纵隔淋巴结刮除术。显微镜检查显示两种肿瘤成分,将典型类癌肿瘤与硬化性肺细胞瘤相关联,同时伴有肿瘤周围实质中存在的弥漫性神经内分泌增生病变。本病例说明了一种罕见肺肿瘤的放射学、大体和显微镜特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dc4/9361798/b23bcf2620c0/CCR3-10-e6237-g004.jpg

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