Siqueira J H, Pereira T S Silva, Moreira A D, Diniz M F H S, Velasquez-Melendez G, Fonseca M J M, Barreto S M, Benseñor I M, Mill J G, Molina M C B
Postgraduate Program in Public Health, Universidade Federal Do Espírito Santo, Marechal Campos Avenue, MaruípeVitória, Espírito Santo, 146829042-755, Brazil.
Health Sciences Department, Universidad de Las Américas Puebla, Cholula, Puebla, México.
J Endocrinol Invest. 2023 Jan;46(1):159-171. doi: 10.1007/s40618-022-01895-3. Epub 2022 Aug 13.
To estimate the association between consumption of sugar-sweetened soft drinks and unsweetened fruit juice with metabolic syndrome (MetS) and its components in participants of the Brazilian Longitudinal Adult Health Study (ELSA-Brasil) after 4 years of follow-up.
We used data from ELSA-Brasil cohort (N = 15,105). The sample consisted of 6,124 civil servants free of the MetS at baseline (35 to 74 years, both sexes). The consumption of sugar-sweetened soft drinks and unsweetened fruit juice was estimated by a food frequency questionnaire previously validated. The outcome was MetS and its components (Joint Interim Statement criteria). To test the association between beverage consumption at baseline (2008-2010) and MetS and its components at follow-up (2012-2014), we used Poisson regression models with robust variance adjusting for potential confounders.
After 4-year follow-up, the higher consumption of sugar-sweetened soft drinks (≥ 1 serving/day = 250 mL/day) increased the relative risk of MetS (RR = 1.22; 95% CI 1.04-1.45), high fasting glucose (RR = 1.23; 95% CI 1.01-1.48), and high blood pressure (RR = 1.23; 95% CI 1.00-1.54). Moderate consumption of this beverage (0.4 to < 1 serving/day) increased the relative risk of high waist circumference (WC) (RR = 1.21; 95% CI 1.02-1.42). After adjustment for confounding variables, the consumption of unsweetened fruit juice was not associated with the MetS and its components.
Higher sugar-sweetened soft drinks consumption was associated with a higher risk relative of MetS, high fasting glucose, and high blood pressure, while moderate consumption of this beverage increased the relative risk of high WC in Brazilian adults.
评估在巴西成人健康纵向研究（ELSA - Brasil）的参与者中，经过4年随访后，含糖软饮料和无糖果汁的摄入量与代谢综合征（MetS）及其组分之间的关联。
我们使用了ELSA - Brasil队列的数据（N = 15105）。样本包括6124名基线时无代谢综合征的公务员（年龄35至74岁，男女皆有）。通过先前验证过的食物频率问卷评估含糖软饮料和无糖果汁的摄入量。结局指标为代谢综合征及其组分（联合临时声明标准）。为检验基线时（2008 - 2010年）饮料摄入量与随访时（2012 - 2014年）代谢综合征及其组分之间的关联，我们使用了泊松回归模型，并对潜在混杂因素进行稳健方差调整。
经过4年随访，较高的含糖软饮料摄入量（≥1份/天 = 250毫升/天）增加了代谢综合征的相对风险（RR = 1.22；95%可信区间1.04 - 1.45）、空腹血糖升高（RR = 1.23；95%可信区间1.01 - 1.48）以及高血压的相对风险（RR = 1.23；95%可信区间1.00 - 1.54）。适度饮用这种饮料（0.4至＜1份/天）增加了高腰围（WC）的相对风险（RR = 1.21；95%可信区间1.02 - 1.42）。在对混杂变量进行调整后，无糖果汁的摄入量与代谢综合征及其组分无关。
较高的含糖软饮料摄入量与代谢综合征、空腹血糖升高和高血压的较高相对风险相关，而适度饮用这种饮料会增加巴西成年人高腰围的相对风险。
