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鼻细胞学检查:精准医学中用于诊断鼻上皮屏障损伤炎症的简便诊断工具。一篇观点性综述。

Nasal Cytology: A Easy Diagnostic Tool in Precision Medicine for Inflammation in Epithelial Barrier Damage in the Nose. A Perspective Mini Review.

作者信息

Caruso Cristiano, Giancaspro Rossana, Guida Giuseppe, Macchi Alberto, Landi Massimo, Heffler Enrico, Gelardi Matteo

机构信息

Unit of Internal Medicine and Gastroenterology, Department of Medical and Surgical Sciences, Agostino Gemelli University Polyclinic (IRCCS), Rome, Italy.

Allergy Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.

出版信息

Front Allergy. 2022 Apr 6;3:768408. doi: 10.3389/falgy.2022.768408. eCollection 2022.

Abstract

Nasal cytology is a diagnostic tool that can be used in precision rhinology medicine. Particularly in non-allergic rhinitis and chronic rhinosinusitis forms it can be useful to evaluate biomarkers of both surgical or biological therapy and especially in the follow-up it must be used to predict the prognostic index of recurrence of nasal polyposis. All inflammatory cytokines are also linked to the presence of cells such as eosinophils and mastcells and nasal cytology is a non-invasive and repeatable method to assess the situation in real life.

摘要

鼻细胞学是一种可用于精准鼻科学医学的诊断工具。特别是在非过敏性鼻炎和慢性鼻-鼻窦炎类型中,它对于评估手术或生物治疗的生物标志物可能有用,尤其是在随访中,它必须用于预测鼻息肉复发的预后指数。所有炎性细胞因子也都与嗜酸性粒细胞和肥大细胞等细胞的存在有关,而鼻细胞学是一种在实际情况中评估病情的非侵入性且可重复的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2ca/9365292/f99b79b84b7d/falgy-03-768408-g0001.jpg

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