瘢痕组织中的弹性纤维：扫描电镜和透射电镜研究

Elastic fibers in scar tissue: scanning and transmission electron microscopic studies.

作者信息

Tsuji T, Sawabe M

出版信息

J Cutan Pathol. 1987 Apr;14(2):106-13. doi: 10.1111/j.1600-0560.1987.tb00481.x.

DOI:10.1111/j.1600-0560.1987.tb00481.x

Abstract

Cutaneous scar tissue (atrophic and hypertrophic) and normal dermis were examined using scanning (SEM) and transmission electron microscopy (TEM) as well as light microscopy (LM). Although LM revealed only a few Weigert stain-positive elastic fibers in scar tissue, SEM and TEM disclosed the presence of a large number of fine elastic fibers which was not present in normal dermis. Atrophic scar tissue contained more Weigert stain-positive fibers and fewer fine elastic fibers than hypertrophic scar tissue. In addition, finding suggestive of newly synthesized elastic fibers were seen in some hypertrophic scar tissue. These results indicate that there is elastogenesis in scar tissue.

摘要

使用扫描电子显微镜（SEM）、透射电子显微镜（TEM）以及光学显微镜（LM）对皮肤瘢痕组织（萎缩性和肥厚性）和正常真皮进行了检查。虽然光学显微镜仅显示瘢痕组织中有少量魏格特染色阳性的弹性纤维，但扫描电子显微镜和透射电子显微镜揭示存在大量正常真皮中不存在的细弹性纤维。萎缩性瘢痕组织比肥厚性瘢痕组织含有更多魏格特染色阳性纤维和更少的细弹性纤维。此外，在一些肥厚性瘢痕组织中发现了提示新合成弹性纤维的迹象。这些结果表明瘢痕组织中存在弹性纤维生成。