起源于巴雷特食管的混合性神经内分泌-非神经内分泌肿瘤

Mixed Neuroendocrine - Nonneuroendocrine Neoplasm Arising in Barrett's Esophagus.

作者信息

Lee Soon Liang, Ng Chiun Yann, Gew Lai Teck, Sidhu Jasminder, Baharom Zuliatul F

机构信息

Department of Medicine, Gastroenterology and Hepatology Unit, Kuala Lumpur General Hospital, Kuala Lumpur, Wilayah Persekutuan, Malaysia.

Department of Pathology, Kuala Lumpur General Hospital, Kuala Lumpur, Wilayah Persekutuan, Malaysia.

出版信息

Euroasian J Hepatogastroenterol. 2022 Jan-Jun;12(1):57-59. doi: 10.5005/jp-journals-10018-1356.

DOI:10.5005/jp-journals-10018-1356

PMID:35990865

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9357519/

Abstract

UNLABELLED

Barrett's esophagus, which results from chronic gastroesophageal reflux disease, is a known precursor to dysplasia and ultimately esophageal adenocarcinoma. Mixed neuroendocrine - nonneuroendocrine neoplasm (MiNEN) is a rare and heterogenous group of neoplasm with aggressive clinical behavior in general. There have been rare reports of MiNEN arising in Barrett's esophagus, and its pathogenesis remains unclear. Surgical resection with lymph node dissection remains the most effective treatment of MiNEN of the esophagus to date, although the evidence on its optimal treatment is scant.

HOW TO CITE THIS ARTICLE

Lee SL, Ng CY, Gew LT, Mixed Neuroendocrine - Nonneuroendocrine Neoplasm Arising in Barrett's Esophagus. Euroasian J Hepato-Gastroenterol 2022;12(1):57-59.

摘要

未标注

巴雷特食管由慢性胃食管反流病引起，是已知的发育异常及最终食管腺癌的前驱病变。混合性神经内分泌-非神经内分泌肿瘤（MiNEN）是一组罕见且异质性的肿瘤，总体具有侵袭性临床行为。巴雷特食管中出现MiNEN的报道罕见，其发病机制仍不清楚。手术切除并清扫淋巴结仍是目前食管MiNEN最有效的治疗方法，尽管关于其最佳治疗的证据不足。