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ICMR 特别工作组项目-印度蛇咬伤的发病率、死亡率、发病率和社会经济负担的调查:研究方案。

ICMR task force project- survey of the incidence, mortality, morbidity and socio-economic burden of snakebite in India: A study protocol.

机构信息

Preventive Cardiology & Population Health Sciences, Amrita Institute of Medical Sciences & Research Centre, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Department of Health & Family Welfare, Shimla, Himachal Pradesh, India.

出版信息

PLoS One. 2022 Aug 22;17(8):e0270735. doi: 10.1371/journal.pone.0270735. eCollection 2022.

Abstract

BACKGROUND

Snakebite is possibly the most neglected of the NTDs (Neglected Tropical Diseases). Half of the global deaths due to venomous snakebites, estimated at 100,000 per year, occur in India. The only representative data on snakebite available from India is the mortality data from the RGI-MDS study (Registrar General of India- 1 Million Death Study) and another study on mortality from the state of Bihar. Incidence data on snakebite is available for 2 districts of the state of West Bengal only. Hospital-based data on snakebite admissions and use of ASV are gross underestimates as most snakebite victims in rural India depend more on alternate treatment methods which do not get represented in National registries. The proposed study is a multi-centric study to determine the incidence, morbidity, mortality and economic burden of snakebites in India covering all 5 geographical zones of the country.

PROTOCOL

A community level surveillance for snakebite covering 31 districts in 13 states of India in order to obtain annual incidence of snakebites from the community. Frontline health workers will be trained to gather information on new cases of snakebite over the study period of 1-year, from "wards "(smallest administrative subunit of a village or town) that they represent in the study districts. Dedicated field officers would collect data on snakebites, victim characteristics, outcomes, utilization of health facilities on a questionnaire sheet designed for this purpose. The study duration is for 18 months from April 2022 to October 2023.

DISCUSSION

The study would be the first of its kind in India looking prospectively at the incidence of snakebite covering 13 states in 5 zones of India and a population of 84 million. Our study covers 6.12% of the total population of the country as compared to the incidence study conducted in Sri Lanka which covered 1% of the total population.

摘要

背景

蛇伤可能是被忽视的热带病(NTDs)中最被忽视的一种。每年全球有 10 万人因毒蛇咬伤而死亡,其中一半发生在印度。印度唯一可用的关于蛇伤的代表性数据是 RGI-MDS 研究(印度人口登记总署-100 万死亡研究)和比哈尔邦的另一项关于死亡率的研究中的死亡数据。仅西孟加拉邦的 2 个地区有关于蛇伤的发病率数据。基于医院的蛇伤入院和使用抗蛇毒血清的数据严重低估了印度农村地区大多数蛇伤受害者更多依赖替代治疗方法的情况,这些方法在国家登记处没有得到体现。拟议的研究是一项多中心研究,旨在确定印度蛇伤的发病率、发病率、死亡率和经济负担,涵盖该国所有 5 个地理区域。

方案

在印度 13 个邦的 31 个地区开展社区级蛇伤监测,以从社区获得每年的蛇伤发病率。将培训一线卫生工作者,以便在研究期间(1 年)收集他们所在研究地区的新蛇伤病例信息。专门的实地工作人员将使用为此目的设计的问卷表收集关于蛇伤、受害者特征、结局和卫生设施使用情况的数据。研究期限为 2022 年 4 月至 2023 年 10 月的 18 个月。

讨论

该研究将是印度首例前瞻性研究,涵盖印度 5 个地区的 13 个邦和 8400 万人口的蛇伤发病率。我们的研究覆盖了全国总人口的 6.12%,而斯里兰卡进行的发病率研究仅覆盖了总人口的 1%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/085f/9394808/aad8f31e6362/pone.0270735.g001.jpg

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