Secondary Metabolites from the Endoparasitic Nematophagous Fungus YMF 1.01751.

, an endoparasitic nematophagous fungus (ENF), is a model fungus from which the genus was established. It can infect nematodes via ingested conidia. In this paper, the morphology and nematode-fungus interaction between and were observed by scanning electron microscopy (SEM). The secondary metabolites of were also studied. Seven metabolites were purified and identified from an ethyl acetate extract of broth and a methanol extract of mycelium. These include a new polyketone 5-hydroxy-3-(hydroxymethyl)-6-methyl-2-pyran-2-one () and six known metabolites (17)-17-methylincisterol (), eburicol (), ergosterol peroxide (), terpendole C (), (3β,5α,9β,22)-3,5-dihydroxy-ergosta-7,22-dien-6-one (), and 5α,6β-epoxy-(22,24)-ergosta-8,22-diene- 3β,7α-diol (). These metabolites were assayed for their activity against plant root-knot nematode, , and the results showed that terpendole C () had weak nematicidal activity but also that other compounds did not have evident activity at a concentration of 400 μg mL. Compound exhibited an attractive effect towards .