关于奥密克戎亚变体 BA.4 和 BA.5 的最新信息。
Update on the omicron sub-variants BA.4 and BA.5.
机构信息
Department of Biology, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Manado, North Sulawesi, Indonesia.
Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa, Saudi Arabia.
出版信息
Rev Med Virol. 2023 Jan;33(1):e2391. doi: 10.1002/rmv.2391. Epub 2022 Aug 26.
Abstract
Several nations have recently begun to relax their public health protocols, particularly regarding the use of face masks when engaging in outdoor activities. This is because there has been a general trend towards fewer cases of coronavirus disease 2019 (COVID-19). However, new Omicron sub-variants (designated BA.4 and BA.5) have recently emerged. These two subvariants are thought to be the cause of an increase in COVID-19 cases in South Africa, the United States, and Europe. They have also begun to spread throughout Asia. They evolved from the Omicron lineage with characteristics that make them even more contagious and which allow them to circumvent immunity from a previous infection or vaccination. This article reviews a number of scientific considerations about these new variants, including their apparently reduced clinical severity.
摘要
最近，有几个国家开始放宽公共卫生协议，特别是在进行户外活动时使用口罩方面。这是因为 2019 年冠状病毒病（COVID-19）的病例总体呈下降趋势。然而，最近出现了新的奥密克戎亚变种（被指定为 BA.4 和 BA.5）。这两种亚变种被认为是导致南非、美国和欧洲 COVID-19 病例增加的原因。它们也开始在亚洲传播。它们是从奥密克戎谱系中进化而来的，具有使其更具传染性的特征，并使其能够规避先前感染或接种疫苗产生的免疫力。本文综述了一些关于这些新变种的科学考虑因素，包括它们明显降低的临床严重程度。
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