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一项评估曲妥珠单抗生物类似药(赫赛汀)联合治疗医生选择方案(TPC)在经大量预处理的 HER2+转移性乳腺癌(KCSG BR 18-14/KM10B)患者中的疗效的 II 期研究。

Phase II study to investigate the efficacy of trastuzumab biosimilar (Herzuma®) plus treatment of physician's choice (TPC) in patients with heavily pretreated HER-2+ metastatic breast cancer (KCSG BR 18-14/KM10B).

机构信息

Center for Breast Cancer, National Cancer Center, Goyang, South Korea.

Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.

出版信息

Breast. 2022 Oct;65:172-178. doi: 10.1016/j.breast.2022.08.002. Epub 2022 Aug 17.

Abstract

We investigated the efficacy and safety of a trastuzumab biosimilar, Herzuma®, in combination with treatment of physician's choice (TPC) in patients with HER2+ metastatic breast cancer (MBC) who had failed at least two HER2 directed chemotherapies.

摘要

我们研究了曲妥珠单抗生物类似药 Herzuma®联合医生选择的治疗方案(TPC)治疗至少两种曲妥珠单抗为基础的化疗失败的 HER2+转移性乳腺癌(MBC)患者的疗效和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5937/9429798/8bceb5eec9f4/gr1.jpg

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