Sawant Vishal D, Karnik Prachi, Viswanathan Varun, Rodrigues Blossom, Fernandes Lavina, Jadhav Alka
Department of Pediatrics, TNMC & BYL Nair Hospital, Mumbai, Maharashtra, India.
Department of Pediatrics, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
Indian J Community Med. 2022 Apr-Jun;47(2):223-228. doi: 10.4103/ijcm.ijcm_954_21. Epub 2022 Jul 11.
The aim of our study was to study and compare the impact and efficacy of medical nutrition therapy (MNT) with that of the standard nutrition therapy(SNT) in children diagnosed with Severe thiness in the age group of 5-10 years and diagnosed as severely thin.
It was a prospective comparative study, conducted over a period of 18 months at the Nutrition Rehabilitation, Research and Training Centre (NRRTC) associated with a tertiary care hospital in India.
A total of 113 children in the age group of 5 to 10 years with severe thinness were enrolled and divided into 2 groups-58 were placed in the MNT group and 55 in the SNT group for a period of 8 weeks. The children in both groups received MNT and SNT diet over the said period of 8 weeks. Primary outcome variables were weight gain and body mass index (BMI) (i.e., change in nutritional status).
At the end of 8 weeks, the rate of weight gain (gm/kg/day) was significantly greater in the MNT group, that is, 2.35 gm/kg/day as compared with the SNT group, that is, 0.73 gm/kg/day, and the change in nutritional status was significantly better in the MNT group (p < 0.001) with 62.1% achieving normal nutritional status, 32.8% remaining thin, and 5.2% remaining severely thin as compared to the SNT group in which 9.1% achieved normal nutritional status, 65.5% remained thin, and 25.5% remained severely thin.
To conclude, MNT is superior to SNT for the treatment of severe thinness (ST).
我们研究的目的是研究并比较医学营养治疗(MNT)与标准营养治疗(SNT)对5至10岁被诊断为重度消瘦的儿童的影响和疗效。
这是一项前瞻性比较研究,在印度一家三级护理医院附属的营养康复、研究和培训中心(NRRTC)进行,为期18个月。
总共招募了113名5至10岁的重度消瘦儿童,并将其分为两组——58名儿童被纳入MNT组,55名儿童被纳入SNT组,为期8周。在这8周内,两组儿童分别接受MNT和SNT饮食。主要结局变量为体重增加和体重指数(BMI)(即营养状况的变化)。
8周结束时,MNT组的体重增加率(克/千克/天)显著更高,即2.35克/千克/天,而SNT组为0.73克/千克/天,并且MNT组的营养状况变化明显更好(p<0.001),62.1%的儿童达到正常营养状况,32.8%仍消瘦,5.2%仍重度消瘦;相比之下,SNT组中9.1%达到正常营养状况,65.5%仍消瘦,25.5%仍重度消瘦。
总之,在治疗重度消瘦(ST)方面,MNT优于SNT。