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社论观点:儿童精神障碍的治疗方法长期有效吗?系统评价综述。

Editorial Perspective: Are treatments for childhood mental disorders helpful in the long run? An overview of systematic reviews.

机构信息

Department of Developmental Psychology, Faculty of Behavioral and Social Sciences, University of Groningen, Groningen, The Netherlands.

Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University Medical Center Groningen (UMCG), University of Groningen, Groningen, The Netherlands.

出版信息

J Child Psychol Psychiatry. 2023 Mar;64(3):464-469. doi: 10.1111/jcpp.13677. Epub 2022 Aug 29.

Abstract

Mental disorders may have severe consequences for individuals across their entire lifespan, especially when they start in childhood. Effective treatments (both psychosocial and pharmacological) exist for the short-term treatment of common mental disorders in young people. These could, at least theoretically, prevent future problems, including recurrence of the disorder, development of comorbidity, or problems in functioning. However, little is known about the actual effects of these treatments in the long run. In the current editorial perspective, we consider the available evidence for the long-term (i.e., ≥2 years) effectiveness and safety of treatments for attention deficit hyperactivity disorder, behavior disorders, and anxiety and depressive disorders for children between 6 and 12 years old. After providing an overview of the literature, we reflect on two key issues, namely, methodological difficulties in establishing long-term treatment effects, and the risk-benefit ratio of treatments for common childhood mental disorders. In addition, we discuss future research possibilities, clinical implications, and other approaches, specifically whole-of-society-actions that could potentially reduce the burden of common childhood mental disorders.

摘要

精神障碍可能会对个人的整个生命周期产生严重后果,尤其是当它们在儿童时期开始时。目前存在有效的心理社会和药物治疗方法,可短期治疗年轻人常见的精神障碍。这些治疗方法至少在理论上可以预防未来的问题,包括疾病复发、共病发展或功能障碍。然而,对于这些治疗方法的长期实际效果知之甚少。在当前的社论观点中,我们考虑了针对 6 至 12 岁儿童的注意力缺陷多动障碍、行为障碍以及焦虑和抑郁障碍的长期(即≥2 年)有效性和安全性的现有证据。在提供文献概述之后,我们反思了两个关键问题,即确定长期治疗效果的方法学困难,以及常见儿童期精神障碍治疗的风险效益比。此外,我们还讨论了未来的研究可能性、临床意义和其他方法,特别是整个社会的行动,这些行动可能会减轻常见儿童期精神障碍的负担。

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