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因危重症 COVID-19 患者腹腔内高压导致静脉-静脉体外膜肺氧合失败而行减压剖腹术。

Decompressive Laparotomy for Veno-Venous Extracorporeal Membrane Oxygenation Failure due to Intra-Abdominal Hypertension in Critically Ill COVID-19 Patient.

机构信息

Department of General Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.

Hebrew University School of Medicine, Jerusalem, Israel.

出版信息

Am Surg. 2023 Dec;89(12):6254-6256. doi: 10.1177/00031348221114520. Epub 2022 Sep 8.

DOI:10.1177/00031348221114520
PMID:36075569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9459369/
Abstract

The use of extracorporeal membrane oxygenation (ECMO) has increased over the course of the SARS-CoV-2 pandemic. Intra-abdominal hypertension resulting in abdominal compartment syndrome (ACS) during ECMO support is a rare but life-threatening complication, with previous case series describing mortality rates of 44%-100%. Bleeding complications, linked to both patient-related and device-related factors, also characterize prolonged ECMO support and have been reported in up to 60% of ECMO patients. We hereby describe a critically ill COVID-19 patient who underwent emergent bed-side decompressive laparotomy for acute ECMO failure related to the development of ACS. The discussion is focused on surgical considerations including the delicate balance between anticoagulation and thrombosis, as anticoagulation-free ECMO support may be required due to hemorrhagic complications.

摘要

在 SARS-CoV-2 大流行期间,体外膜肺氧合(ECMO)的使用有所增加。在 ECMO 支持过程中,由于腹内压升高导致腹腔间隔室综合征(ACS)是一种罕见但危及生命的并发症,以前的病例系列报告死亡率为 44%-100%。出血并发症与患者相关和设备相关因素均有关联,也是 ECMO 支持时间延长的特征,据报道,多达 60%的 ECMO 患者会发生这种情况。在此,我们描述了一位重症 COVID-19 患者,他因 ACS 发展导致急性 ECMO 失败而紧急床边减压剖腹术。讨论重点是手术注意事项,包括抗凝和血栓形成之间的微妙平衡,因为由于出血并发症,可能需要无抗凝 ECMO 支持。

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