Atli Baran, Rath Sebastian, Burtscher Johannes, Hainfellner Johannes A, Hametner Simon
1Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria; and.
2Department of Neurosurgery, Wiener Neustadt State Hospital, Wiener Neustadt, Austria.
J Neurosurg Case Lessons. 2022 Aug 8;4(6). doi: 10.3171/CASE2270.
Encephaloceles are protrusions of the cerebral tissue through a skull defect. They occur mostly in children and very rarely in adults.
The authors present a case of a 44-year-old man presenting with a first-time generalized seizure. Computed tomography of the head showed bone destruction associated with a right frontal lesion. Magnetic resonance imaging scans demonstrated a largely isointense lesion in the intradiploic space that contained small, hyperintense nodular components and showed a low to moderate contrast agent enhancement.
The patient underwent resection, during which the histological examination found the lesion to be an intradiploic encephalocele. The patient had an uneventful postoperative course with a cessation of seizures. The imaging and neuropathological findings as well as a literature review, together with a discussion on the etiology of intradiploic encephaloceles, are contained in this report.
脑膨出是脑组织通过颅骨缺损处的突出。多见于儿童,成人极为罕见。
作者报告一例44岁男性,首次出现全身性癫痫发作。头部计算机断层扫描显示与右侧额叶病变相关的骨质破坏。磁共振成像扫描显示板障内有一个大致等信号病变,其中包含小的高信号结节成分,对比剂增强呈低至中度。
患者接受了切除术,术中组织学检查发现病变为板障内脑膨出。患者术后恢复顺利,癫痫发作停止。本报告包含影像学和神经病理学发现、文献综述以及关于板障内脑膨出病因的讨论。