Kadado Anis John, Chalhoub Fadi
UMass Chan Medical School - Baystate, Department of Cardiology, Springfield, MA, USA.
UMass Chan Medical School - Baystate, Department of Cardiology, Springfield, MA, USA.
Int J Cardiol. 2023 Jan 15;371:221-225. doi: 10.1016/j.ijcard.2022.09.027. Epub 2022 Sep 15.
Over the past decade, there has been significant improvement in the treatment cardiac diseases and symptomatic bradyarrhythmias with the development of leadless pacemaker systems. The Micra transcatheter pacemaker system has been shown to mitigate a lot of the complications associated with traditional pacing systems, which are notably skin pocket and lead-related complications. Numerous studies have shown the low complication rates associated with Micra procedure; however, there have been no specific guidelines or recommendations surrounding periprocedural anticoagulant therapy. This is important because a significant percentage of patients requiring pacemaker therapy have an indication for anticoagulation therapy as well. Multiple studies have shown the safety of uninterrupted anticoagulation during Micra implant, however, there is insufficient high-quality data to recommend periprocedural systemic use of anticoagulation. In this paper, we review the available data surrounding anticoagulation therapy in patients undergoing Micra implantation and the potential bleeding risks associated with this procedure.
在过去十年中,随着无导线起搏器系统的发展,心脏病和症状性缓慢性心律失常的治疗有了显著改善。Micra经导管起搏器系统已被证明能减轻许多与传统起搏系统相关的并发症,尤其是皮囊和导线相关的并发症。大量研究表明Micra手术的并发症发生率较低;然而,对于围手术期抗凝治疗,尚无具体的指南或建议。这一点很重要,因为需要起搏器治疗的患者中有很大一部分也有抗凝治疗的指征。多项研究表明,在植入Micra期间不间断抗凝是安全的,然而,没有足够的高质量数据来推荐围手术期全身使用抗凝剂。在本文中,我们回顾了有关接受Micra植入患者抗凝治疗的现有数据以及该手术潜在的出血风险。