González V Laura, Cardozo S Olivia, Samudio A Margarita, Mesquita R Mirta
Hospital General Pediátrico "Niños de Acosta Ñu", San Lorenzo, Paraguay.
Universidad del Pacifico, Asunción, Paraguay.
Rev Chilena Infectol. 2022 Jun;39(3):265-272. doi: 10.4067/s0716-10182022000200265.
Ocular toxoplasmosis (OT) is a retinochoroiditis that evolves with several episodes of inflammation and can occur both in the congenital or acquired form of the disease, Aim: To describe the frequency and clinical characteristics of OT in infants aged 0 to 12 months, children of mothers with positive serology for toxoplasmosis in the perinatal period.
Cross-sectional descriptive, ambispective study.
Infants from 0 to 12 months of age, whose mothers had positive serology for toxoplasmosis in the perinatal period, referred to the pediatric ophthalmology service for evaluation, were admitted. Demographic variables, maternal and infant serology and the results of the ophthalmological examination were collected. Data were analyzed in SPSS v21 Results: 46.4% of 125 infants had OT, of them 67.2% were female, (p = 0.04) the median age was 6 months, 41% had IgG and IgM positive. The lesions were bilateral in 82.8%, central in 86.2%, and inactive in 81%. Retinochoroiditis was accompanied by strabismus in 41%.
The frequency of OT in this population of infants with congenital toxoplasmosis was high. more than 80% of the eye lesions were inactive, centrally located and bilaterally involved.
眼弓形虫病(OT)是一种视网膜脉络膜炎,伴有多次炎症发作,可表现为先天性或后天性疾病形式。目的:描述0至12个月婴儿中OT的发病率及临床特征,这些婴儿的母亲在围产期弓形虫血清学检查呈阳性。
横断面描述性、双向性研究。
将0至12个月、母亲在围产期弓形虫血清学检查呈阳性、因评估转诊至小儿眼科服务的婴儿纳入研究。收集人口统计学变量、母婴血清学及眼科检查结果。数据在SPSS v21中进行分析。结果:125例婴儿中46.4%患有OT,其中67.2%为女性,(p = 0.04)中位年龄为6个月,41%的婴儿IgG和IgM呈阳性。82.8%的病变为双侧性,86.2%为中央性,81%为静止性。41%的视网膜脉络膜炎伴有斜视。
在这群先天性弓形虫病婴儿中OT的发病率较高。超过80%的眼部病变为静止性、位于中央且双侧受累。