University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Ophthalmology, University of Virginia Health System, Charlottesville, Virginia, USA.
BMJ Open Ophthalmol. 2022 Jul;7(1). doi: 10.1136/bmjophth-2021-000894.
To examine outcomes of different surgical modalities for correcting primary rhegmatogenous retinal detachments in patients younger than 50 years of age.
A single-centre, retrospective, cohort study of 754 patients who underwent retinal surgery at the University of Virginia Hospital between 1 July 2012 and 1 July 2020 was conducted. Exclusion criteria were patients less than 18 or over 50 years of age, repeat detachments, second eyes of patients with bilateral detachments and follow-up less than 3 months. A multivariate regression model was used to compare overall outcomes in patients.
86 patients met inclusion criteria and of those, 38 (44%) underwent vitrectomy, 22 (26%) underwent scleral buckling, 13 (15%) underwent pneumatic retinopexy and 13 (15%) underwent combined scleral buckle and vitrectomy repair. Comparison of eye-level parameters among the procedure groups shows difference with respect to macular involvement (p<0.05) but not regarding clock hour involvement or giant tear status (p>0.05). Preoperative visual acuity was superior in the scleral buckle group compared with vitrectomy (p<0.001). Mean postoperative visual acuity improved with all procedures and all repair procedures had comparable rates of complication. The mean overall anatomical success rate was 73% (n=63) and comparable among all modalities.
Vitrectomy, scleral buckle, pneumatic retinopexy or combined procedures are viable repair options for rhegmatogenous retinal detachments in patients younger than 50 years of age. Selection of the repair modality should be guided on baseline clinical features of the patient and detachment.
研究不同手术方式治疗 50 岁以下原发性孔源性视网膜脱离患者的结局。
对 2012 年 7 月 1 日至 2020 年 7 月 1 日在弗吉尼亚大学医院接受视网膜手术的 754 例患者进行了一项单中心回顾性队列研究。排除标准为年龄小于 18 岁或大于 50 岁、复发性脱离、双眼患者的第二只眼有脱离、随访时间少于 3 个月。使用多变量回归模型比较患者的总体结局。
86 例患者符合纳入标准,其中 38 例(44%)行玻璃体切除术,22 例(26%)行巩膜扣带术,13 例(15%)行充气性视网膜固定术,13 例(15%)行巩膜扣带术联合玻璃体切除术。对各手术组眼部参数进行比较,发现黄斑受累程度存在差异(p<0.05),但时钟小时受累程度或大裂孔状态无差异(p>0.05)。与玻璃体切除术相比,巩膜扣带术组术前视力较好(p<0.001)。所有手术均能提高术后平均视力,所有修复术式的并发症发生率相似。总体解剖成功率的平均值为 73%(n=63),各术式间无差异。
玻璃体切除术、巩膜扣带术、充气性视网膜固定术或联合手术是治疗 50 岁以下孔源性视网膜脱离患者的可行修复选择。修复方式的选择应根据患者的基线临床特征和脱离情况进行指导。