The Second Department of Gynaecology, Central Hospital of City Handan, Handan 056001, Hebei, China.
Contrast Media Mol Imaging. 2022 Sep 16;2022:6129817. doi: 10.1155/2022/6129817. eCollection 2022.
In order to solve the problem of early differential diagnosis of ovarian cancer, this paper proposes the role of bioinformatics analysis in early differential diagnosis of ovarian cancer. This method uses bioinformatics methods to mine the existing data in the tumor database and obtain tumor-related molecules. It is an efficient method to obtain effective biomarkers, screen signal pathway molecules, and reveal the internal mechanism of tumor occurrence and development. Using this method can greatly improve the efficiency and reliability of screening diagnosis, prognosis, and treatment targets. The results showed that 5821 new lncRNA transcripts and 4611 new lncRNA genes were identified by lncScore from the assembled transcripts. 10 new lncRNA transcripts and 174 new lncRNA genes were found to be differentially expressed in ovarian cancer.
为了解决卵巢癌的早期鉴别诊断问题,本文提出了生物信息学分析在卵巢癌早期鉴别诊断中的作用。该方法利用生物信息学方法挖掘肿瘤数据库中现有的数据,获得肿瘤相关分子,是获取有效生物标志物、筛选信号通路分子、揭示肿瘤发生发展内在机制的有效方法。使用这种方法可以大大提高筛选诊断、预后和治疗靶点的效率和可靠性。结果表明,通过 lncScore 从组装的转录本中鉴定出 5821 个新的 lncRNA 转录本和 4611 个新的 lncRNA 基因。在卵巢癌中发现 10 个新的 lncRNA 转录本和 174 个新的 lncRNA 基因表达差异。