刷牙习惯与 COVID-19 症状之间的关联。

Association Between Toothbrushing Habits and COVID-19 Symptoms.

机构信息

Department of International and Community Oral Health, Tohoku University, Graduate School of Dentistry, Sendai, Japan.

出版信息

Int Dent J. 2023 Apr;73(2):302-310. doi: 10.1016/j.identj.2022.07.011. Epub 2022 Aug 4.

DOI:10.1016/j.identj.2022.07.011

PMID:36192224

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9350673/

Abstract

OBJECTIVES

The association between toothbrushing and coronavirus disease 2019 (COVID-19) infections is unknown. The aim of this study was to test the hypothesis that the change in time and frequency of toothbrushing is associated with having COVID-19 symptoms.

METHODS

In this 8-month retrospective cohort study, we used the data from the Japan COVID-19 and Society Internet Survey (JACSIS; N = 22,366), which was conducted between August and September 2020. The logistic regression analyses were used to calculate the odds ratios (ORs) of having the 3 main COVID-19 symptoms (high fever, cough, and taste and smell disorder). Confounders were age, sex, educational attainment, equivalised income level, self-rated health, health literacy, and living area.

RESULTS

The mean age of the participants was 49 years (SD = ±17.3), and 49.2% were male. Overall 2704 (12.1%) participants changed (increased or decreased) the time and frequency of toothbrushing, whilst 19,662 (87.9%) did not change. Only 60 participants (0.3%) had the 3 main COVID-19 symptoms. All logistic regression models showed that those who had a change in time and frequency of toothbrushing had higher odds of having the 3 main COVID-19 symptoms compared to those who had unchanged time and frequency of toothbrushing. The ORs ranged from 6.00 (95% confidence interval [CI], 3.60-9.99) in the crude model to 4.08 (95% CI, 2.38-6.98) in the fully adjusted model.

CONCLUSIONS

The change in time and frequency of toothbrushing from before to after the COVID-19 pandemic was associated with having the 3 main COVID-19 symptoms.

摘要

目的

目前尚不清楚刷牙与 2019 年冠状病毒病（COVID-19）感染之间的关联。本研究旨在检验以下假设，即刷牙时间和频率的变化与出现 COVID-19 症状有关。

方法

本 8 个月回顾性队列研究使用了 2020 年 8 月至 9 月期间开展的日本 COVID-19 和社会互联网调查（JACSIS）的数据（N=22366）。采用逻辑回归分析计算出现 COVID-19 的 3 种主要症状（高热、咳嗽和味觉嗅觉障碍）的优势比（OR）。混杂因素为年龄、性别、受教育程度、等效收入水平、自我评估健康状况、健康素养和居住地区。

结果

参与者的平均年龄为 49 岁（SD±17.3），49.2%为男性。总体而言，有 2704 名（12.1%）参与者改变（增加或减少）了刷牙时间和频率，19662 名（87.9%）参与者未改变。仅有 60 名参与者（0.3%）出现了 COVID-19 的 3 种主要症状。所有逻辑回归模型均显示，与刷牙时间和频率未改变的参与者相比，改变刷牙时间和频率的参与者出现 COVID-19 的 3 种主要症状的可能性更高。OR 范围从未调整模型中的 6.00（95%置信区间[CI]，3.60-9.99）到完全调整模型中的 4.08（95% CI，2.38-6.98）。