Rp1的合生元微胶囊化：一种从拉吉粥中分离出的具有抗结肠癌细胞系增殖特性的潜在益生菌。
Synbiotic microencapsulation of Rp1: a potential probiotic isolated from ragi porridge with antiproliferative property against colon carcinoma cell line.
作者信息
Ashwanandhini Govindarajan, Reshma Raveendran, Preetha R
机构信息
Department of Food Process Engineering, School of Bioengineering, The college of Engineering and Technology, SRM Institute of Science and Technology, SRM Nagar, Chengalpattu District, 603203 Kattankulathur, Chennai, Tamil Nadu India.
出版信息
J Food Sci Technol. 2022 Oct;59(10):3888-3894. doi: 10.1007/s13197-022-05415-2. Epub 2022 Apr 6.
UNLABELLED
Ragi porridge, commonly consumed in South India is made from finger millet and noiyee (broken rice), and it is one of the excellent sources for probiotic bacteria. assays provided the proof that the probiotic strains isolated from ragi porridge can survive during the intestinal passage. Also, it showed antioxidant activity and antagonistic activity against foodborne pathogens including and . Rp1 isolated from ragi porridge was susceptible to vancomycin and showed to cease the progression of HCT116 (colon carcinoma) cell line. Further, was microencapsulated using sodium alginate and aloe vera gel as binding agents and onion extract as a source of prebiotic to perform symbiotic encapsulation. In short, this study concludes that the fermented Ragi porridge is a rich source of probiotics with anti-microbial, antioxidant and antiproliferative property hence can be suggested for improving gut microbiota.
SUPPLEMENTARY INFORMATION
The online version contains supplementary material available at 10.1007/s13197-022-05415-2.
未标注
印度南部常见的拉吉粥由黍和碎米制成，是益生菌的优质来源之一。实验证明，从拉吉粥中分离出的益生菌菌株能够在肠道中存活。此外，它还具有抗氧化活性以及对包括[具体病原体1]和[具体病原体2]在内的食源性病原体的拮抗活性。从拉吉粥中分离出的Rp1对万古霉素敏感，并显示出能抑制HCT116（结肠癌细胞系）细胞系的进展。此外，使用海藻酸钠和芦荟凝胶作为粘合剂，洋葱提取物作为益生元来源对[具体物质]进行微囊化，以实现共生包囊。简而言之，本研究得出结论，发酵后的拉吉粥富含具有抗菌、抗氧化和抗增殖特性的益生菌，因此建议食用以改善肠道微生物群。
补充信息
在线版本包含可在10.1007/s13—197—022—05415—2获取的补充材料。
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