Suppr超能文献

中国荆门地区 COVID-19 德尔塔变异株的临床特征。

Clinical characteristics of the delta variant of COVID-19 in Jingmen, China.

机构信息

Department of Dermatology, The First People's Hospital of Jingmen, Jingmen, Hubei Province, P.R. China.

Emergency Department, Jingzhou Central Hospital, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei Province, P.R. China.

出版信息

Medicine (Baltimore). 2022 Sep 23;101(38):e30812. doi: 10.1097/MD.0000000000030812.

Abstract

There has been an epidemic of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) delta variant in Jingmen, China, and the clinical and epidemiological characteristics of all patients infected with SARS-CoV-2 delta variant in an epidemic are rarely reported. All the coronavirus disease 2019 (COVID-19) patients diagnosed in Jingmen in August 2021 were enrolled in this study. Epidemiological data and clinical characteristics were analyzed. Of 58 patients (38 male and 20 female), 11 were children. The mean age was 35 years, and the median age was 39 years (range, 1-60 years; interquartile range, 28-51). The infectivity of the SARS-CoV-2 Delta variant may have increased, but pathogenicity could have decreased significantly. The vast majority of patients had either no symptoms or mild symptoms. Even though the variant virus is highly contagious, control measures have proven effective. Symptoms included fever (53%), cough (48%), headache (6%), runny nose (13%), loss of smell and taste (6%), elevated C-reactive protein (26%), increased neutrophil count (13%), decreased eosinophil count (21%), and elevated mononuclear granulocytes (26%). Thirty-eight of the 47 adults showed lymphocyte decline, but none of the children showed a significant decline, and more than half of them showed an increase. Thirty patients had no pneumonia, 27 patients had mild pneumonia, and only one patient with multiple chronic diseases had severe pneumonia. None of the 11 children had been vaccinated, 10 did not have pneumonia, and 1 had a small lung lesion. The number of new patients disappeared in 15 days after the lockdown of the city.

摘要

中国荆门市出现了严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)Delta 变异株流行,流行期间所有感染 SARS-CoV-2 Delta 变异株患者的临床和流行病学特征鲜有报道。本研究纳入了 2021 年 8 月在荆门市诊断的所有 2019 年冠状病毒病(COVID-19)患者。分析了流行病学数据和临床特征。58 例患者中(男 38 例,女 20 例),有 11 例为儿童。患者平均年龄为 35 岁,中位数年龄为 39 岁(范围 1-60 岁;四分位距 28-51)。SARS-CoV-2 Delta 变异株的传染性可能增加,但致病性可能显著降低。绝大多数患者无症状或症状轻微。尽管变异病毒具有高度传染性,但控制措施已被证明是有效的。症状包括发热(53%)、咳嗽(48%)、头痛(6%)、流涕(13%)、嗅觉味觉丧失(6%)、C 反应蛋白升高(26%)、中性粒细胞计数增加(13%)、嗜酸性粒细胞计数减少(21%)和单核细胞增多(26%)。47 例成人中有 38 例出现淋巴细胞减少,但儿童无一例明显减少,且半数以上患儿淋巴细胞增多。30 例患者无肺炎,27 例患者肺炎较轻,仅有 1 例合并多种慢性疾病的患者肺炎较重。11 例儿童均未接种疫苗,10 例无肺炎,1 例患儿肺部有小病灶。城市封锁后 15 天内新发病例消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/592a/9509070/2420fab717bf/medi-101-e30812-g001.jpg

相似文献

1
Clinical characteristics of the delta variant of COVID-19 in Jingmen, China.
Medicine (Baltimore). 2022 Sep 23;101(38):e30812. doi: 10.1097/MD.0000000000030812.
2
[Clinical features of 19 children infected with the Omicron variant of severe acute respiratory syndrome coronavirus 2 in Hangzhou, China].
Zhongguo Dang Dai Er Ke Za Zhi. 2022 Oct 15;24(10):1092-1097. doi: 10.7499/j.issn.1008-8830.2205122.
3
Clinical characteristics of acute respiratory syndrome with SARS-CoV-2 infection in children in South China.
Pediatr Pulmonol. 2020 Sep;55(9):2419-2426. doi: 10.1002/ppul.24921. Epub 2020 Jul 3.
4
Clinical characteristics of coronavirus disease 2019 in Gansu province, China.
Ann Palliat Med. 2020 Jul;9(4):1404-1412. doi: 10.21037/apm-20-887. Epub 2020 Jul 13.
6
The epidemiological characteristics of 2019 novel coronavirus diseases (COVID-19) in Jingmen, Hubei, China.
Medicine (Baltimore). 2020 Jun 5;99(23):e20605. doi: 10.1097/MD.0000000000020605.
7
Clinical features of Omicron variant infection in 445 patients with coronavirus 19 disease.
Ann Saudi Med. 2023 May-Jun;43(3):161-165. doi: 10.5144/0256-4947.2023.27.03.1300. Epub 2023 Jun 1.
8
Clinical Characteristics of Patients with Severe Pneumonia Caused by the SARS-CoV-2 in Wuhan, China.
Respiration. 2020;99(8):649-657. doi: 10.1159/000507940. Epub 2020 Aug 25.
9
SARS-CoV-2 Delta Variant in Jingmen City, Hubei Province, China, 2021: Children Susceptible and Vaccination Breakthrough Infection.
Front Microbiol. 2022 Apr 13;13:856757. doi: 10.3389/fmicb.2022.856757. eCollection 2022.

引用本文的文献

1
Eosinopenia predicts poor outcomes in patients with lung cancer with the omicron variant of COVID-19.
Front Med (Lausanne). 2025 Jul 9;12:1583843. doi: 10.3389/fmed.2025.1583843. eCollection 2025.

本文引用的文献

1
A Chess and Card Room-Induced COVID-19 Outbreak and Its Agent-Based Simulation in Yangzhou, China.
Front Public Health. 2022 Jun 17;10:915716. doi: 10.3389/fpubh.2022.915716. eCollection 2022.
3
Analysis of the Delta Variant B.1.617.2 COVID-19.
Clin Pract. 2021 Oct 21;11(4):778-784. doi: 10.3390/clinpract11040093.
5
SARS-CoV-2 Variants of Concern.
Yonsei Med J. 2021 Nov;62(11):961-968. doi: 10.3349/ymj.2021.62.11.961.
6
SARS-CoV-2 Delta Variant among Asiatic Lions, India.
Emerg Infect Dis. 2021 Oct;27(10):2723-2725. doi: 10.3201/eid2710.211500.
8
Rapid spread of the SARS-CoV-2 Delta variant in some French regions, June 2021.
Euro Surveill. 2021 Jul;26(28). doi: 10.2807/1560-7917.ES.2021.26.28.2100573.
9
SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness.
Lancet. 2021 Jun 26;397(10293):2461-2462. doi: 10.1016/S0140-6736(21)01358-1. Epub 2021 Jun 14.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验