超敏性肺炎的更新影像分类

Updated Imaging Classification of Hypersensitivity Pneumonitis.

作者信息

Chelala Lydia, Adegunsoye Ayodeji, Cody Brittany A, Husain Aliya N, Chung Jonathan H

机构信息

The University of Chicago Medicine, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

出版信息

Radiol Clin North Am. 2022 Nov;60(6):901-913. doi: 10.1016/j.rcl.2022.06.013. Epub 2022 Sep 7.

DOI:10.1016/j.rcl.2022.06.013

PMID:36202477

Abstract

Hypersensitivity pneumonia (HP) refers to a heterogeneous group of interstitial lung diseases resulting from a non-IgE immune-mediated reaction to inhaled pathogens in susceptible and sensitized hosts. Environmental and genetic factors are important substrates of disease pathogenesis. A recurrent or ongoing airborne exposure results in activation of humoral and cellular immune responses. This article discusses key clinical, radiologic, and histopathologic features of HP and reviews current recommendations.

摘要

过敏性肺炎（HP）是指一组异质性间质性肺疾病，由易感且致敏宿主对吸入病原体的非IgE免疫介导反应引起。环境和遗传因素是疾病发病机制的重要基础。反复或持续的空气传播暴露会导致体液和细胞免疫反应的激活。本文讨论了HP的关键临床、放射学和组织病理学特征，并回顾了当前的建议。