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弥漫性大B细胞淋巴瘤患者的脾结肠瘘:一例病例报告及文献复习

Splenocolic fistula in a patient with diffuse large B-cell lymphoma: A case report and review of literature.

作者信息

Luca Tonia, Sergi Mauro, Coco Onella, Leone Emanuela, Chisari Giulia, Fontana Paolo, Castorina Sergio

机构信息

Department of Medical, Surgical Sciences and Advanced Technologies G.F. Ingrassia, University of Catania, Catania, Italy.

Department of Experimental Oncology, Mediterranean institute of Oncology, Viagrande, Catania, Italy.

出版信息

Front Surg. 2022 Sep 20;9:979463. doi: 10.3389/fsurg.2022.979463. eCollection 2022.

Abstract

A fistula that connects the bowel to other organs, such as the urinary bladder or small intestine, is a relatively frequent complication, often associated with inflammatory diseases such as diverticulitis, Crohn's disease, colorectal cancer, or lymphoma. Splenocolic fistula is an extremely rare condition described in the literature. It can occur in cases of splenic tumors, including splenic diffuse large B cell lymphoma. We report the case of an 82-year-old man who presented with melaena, worsening asthenia, hypotension, and abdominal pain in the left flank and the ipsilateral lumbar region. Ultrasound and computed tomography documented splenomegaly, thickening of the splenic flexure of the colon, and the presence of a fistulous passage between the colon and the splenic hilum. The diagnosis of lymphoma was made following laparotomy and caudal splenopancreatectomy. Due to the aggressive clinical behavior of this type of lymphoma, splenectomy is the main treatment in patients with splenomegaly, abdominal pain, and tumor expansion.

摘要

一种将肠道与其他器官(如膀胱或小肠)相连的瘘管是一种相对常见的并发症,通常与憩室炎、克罗恩病、结直肠癌或淋巴瘤等炎症性疾病有关。脾结肠瘘是文献中描述的一种极其罕见的病症。它可发生于脾脏肿瘤病例,包括脾脏弥漫性大B细胞淋巴瘤。我们报告一例82岁男性患者,其表现为黑便、乏力加重、低血压以及左侧胁腹和同侧腰部疼痛。超声和计算机断层扫描显示脾肿大、结肠脾曲增厚以及结肠与脾门之间存在瘘管通道。剖腹手术及脾胰尾切除术后诊断为淋巴瘤。由于这类淋巴瘤具有侵袭性临床行为,脾切除术是脾肿大、腹痛及肿瘤扩展患者的主要治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e73/9530245/5bd2e13b96e1/fsurg-09-979463-g001.jpg

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