Division of Social Worker, Zhongshan Polytechnic, No.25 Bo'ai 7th Road, East District, Zhongshan City, Guangdong Province, People's Republic of China.
School of Nursing, Tung Wah College, Ma Kam Chan Memorial Building, 31 Wylie Road, Hong Kong SAR, China.
BMC Geriatr. 2022 Oct 7;22(1):788. doi: 10.1186/s12877-022-03437-1.
The early identification of pre-frailty and frailty among older people is a global priority because of the increasing incidence of frailty and associated adverse health outcomes. This study aimed to validate the Groningen Frailty Indicator-Chinese (GFI-C), a widely used screening instrument, and determine the optimal cut-off value in Chinese communities to facilitate pre-frailty and frailty screening.
This methodological study employed a cross-sectional and correlational design to examine the psychometric properties of GFI-C, namely, internal consistency, stability, and concurrent and construct validities. The appropriate cut-off values for pre-frailty and frailty screening in the receiver-operating characteristic (ROC) curve were determined through sensitivity and specificity analysis.
A total of 350 community older people had been assessed and interviewed by a nurse. The GFI-C showed satisfactory internal consistency (Cronbach's α = 0.87) and two-week test-retest reliability (intra-class correlation coefficient = 0.87). Concurrent validity (r = 0.76, p < 0.001) showed a moderate correlation with Fried's frailty phenotype. The known-groups method, hypothesis testing and confirmatory factory analysis (three-factor model; χ/df = 2.87, TLI = 0.92, CFI = 0.93, GFI = 0.92, RMR = 0.014; RMSEA = 0.073) were suitable for the establishment of construct validity. Based on the ROC and Youden's index, the optimal cut-off GFI-C values were 2 (sensitivity, 71.5%; specificity, 84.7%) for pre-frailty and 3 for frailty (sensitivity, 88.2%; specificity, 79.6%).
The result indicated that GFI-C is a reliable and valid instrument for pre-frailty and frailty screening among older Chinese people in communities. For optimal diagnostic accuracy, the cut-off values of 3 for frailty and 2 for pre-frailty are recommended.
由于衰弱的发病率不断增加以及与之相关的不良健康后果,及早识别老年人的衰弱前期和衰弱是全球的优先事项。本研究旨在验证广泛使用的筛查工具——格罗宁根衰弱指标-中文(GFI-C),并确定其在中国社区中用于衰弱前期和衰弱筛查的最佳截断值。
本方法学研究采用横断面和相关性设计,检验 GFI-C 的心理测量学特性,即内部一致性、稳定性、同时和结构有效性。通过灵敏度和特异性分析确定 ROC 曲线中衰弱前期和衰弱筛查的适当截断值。
共有 350 名社区老年人由护士进行评估和访谈。GFI-C 显示出令人满意的内部一致性(Cronbach's α=0.87)和两周重测信度(组内相关系数=0.87)。同时效度(r=0.76,p<0.001)与 Fried 的衰弱表型呈中度相关。已知组方法、假设检验和验证性因子分析(三因素模型;χ/df=2.87,TLI=0.92,CFI=0.93,GFI=0.92,RMR=0.014;RMSEA=0.073)适用于结构有效性的建立。基于 ROC 和 Youden 的指数,最佳截断 GFI-C 值为 2(灵敏度为 71.5%,特异性为 84.7%)用于衰弱前期,3 用于衰弱(灵敏度为 88.2%,特异性为 79.6%)。
结果表明,GFI-C 是一种可靠和有效的社区中老年人衰弱前期和衰弱筛查工具。为了获得最佳的诊断准确性,建议将衰弱的截断值设为 3,衰弱前期的截断值设为 2。