Wittenberg Eve, Labutte Collin, Thornburg Benjamin, Gebreselassie Abraham, Barbosa Carolina, Bray Jeremy W
Center for Health Decision Science, Harvard TH Chan School of Public Health, 718 Huntington Avenue, 02115, Boston, MA, USA.
Bryan School of Business and Economics, University of North Carolina, 462-D Bryan Building, PO Box 26710, 27402-6170, Greensboro, NC, USA.
J Patient Rep Outcomes. 2022 Oct 10;6(1):106. doi: 10.1186/s41687-022-00516-0.
Alcohol consumption has changed during the COVID-19 pandemic yet the impacts on alcohol-related outcomes, and specifically health-related quality of life, are not completely known. Our objective was to assess the association between alcohol consumption and health-related quality of life (HRQOL) during the COVID-19 pandemic.
We conducted an on-line/telephone survey of three cross-sectional samples of US adults during a nine-month stretch of the pandemic, from August 2020 through April 2021, collecting data on drinking-current quantity/frequency and change since prior to pandemic, HRQOL (using the SF-6D), and perceived impact of the pandemic on respondents' lives-overall impact and disruptions across various dimensions (job loss, school closures, social isolation, loss of income). We pooled the data from the three administrations and applied survey weights to reflect the US population. We described drinking behavior and pandemic impact, and regressed HRQOL on alcohol consumption risk level (per World Health Organization categories), change in drinking since pre-pandemic, and pandemic impact using weighted least squares, controlling for respondents' demographic characteristics. We tested the significance of categorical variables using Wald tests at a p-value of 0.05.
Among 3,125 respondents, weighted to reflect the US population, 68% reported drinking during the pandemic and 40% reported a change in drinking from pre-pandemic level (either increased or decreased). Mean HRQOL among our sample was 0.721 (SD 0.003). Any change in drinking from pre-pandemic level was independently associated with significantly lower HRQOL compared to never drinking (pre or during pandemic), from - 0.0251 points for decreased/stopped drinking to -0.0406 points for increased drinking (combined levels' Wald test F = 10.62, p < 0.0000). COVID-19 pandemic related impacts/disruptions were associated with HRQOL decrements ranging from - 0.0834 to -0.1340 (Wald test F = 64.34, p < 0.0000).
The US population HRQOL was substantially lower during the pandemic than reported a decade earlier (mean = 0.79 in 2012-13). While pandemic-related impacts and disruptions may explain a large part of this decrement, changes in drinking-and the associated implications of such changes-might also play a role. Both individuals who reduced their drinking during the pandemic and those who increased consumption may be at risk of poor HRQOL.
在新冠疫情期间,酒精消费情况发生了变化,但对与酒精相关的后果,尤其是与健康相关的生活质量的影响尚不完全清楚。我们的目标是评估新冠疫情期间酒精消费与健康相关生活质量(HRQOL)之间的关联。
在2020年8月至2021年4月这九个月的疫情期间,我们对美国成年人的三个横断面样本进行了在线/电话调查,收集了当前饮酒量/频率以及自疫情前以来的变化、HRQOL(使用SF-6D),以及疫情对受访者生活的感知影响——包括总体影响和各个维度的干扰(失业、学校关闭、社会隔离、收入损失)。我们汇总了三次调查的数据并应用调查权重以反映美国人口情况。我们描述了饮酒行为和疫情影响,并使用加权最小二乘法,将HRQOL对酒精消费风险水平(按照世界卫生组织的分类)、自疫情前以来的饮酒变化以及疫情影响进行回归分析,同时控制受访者的人口统计学特征。我们使用p值为0.05的Wald检验来检验分类变量的显著性。
在3125名经加权以反映美国人口的受访者中,68%报告在疫情期间饮酒,40%报告饮酒量与疫情前水平相比有变化(增加或减少)。我们样本中的平均HRQOL为0.721(标准差0.003)。与从未饮酒(疫情前或疫情期间)相比,与疫情前水平相比饮酒量的任何变化都与显著更低的HRQOL独立相关,饮酒减少/停止的为-0.0251分,饮酒增加的为-0.0406分(合并水平的Wald检验F = 10.62,p < 0.0000)。与新冠疫情相关的影响/干扰与HRQOL下降幅度在-0.0834至-0.1340之间相关(Wald检验F = 64.34,p < 0.0000)。
疫情期间美国人口的HRQOL大幅低于十年前报告的水平(2012 - 2013年平均为0.79)。虽然与疫情相关的影响和干扰可能解释了这种下降的很大一部分,但饮酒的变化以及此类变化的相关影响也可能起作用。在疫情期间减少饮酒的人和饮酒增加的人都可能面临HRQOL较差的风险。