黄体出血合并获得性血友病 A：病例报告及文献复习。
Corpus luteum hemorrhage with acquired hemophilia A: a case report and literature review.
机构信息
Department of Gynecology, Jieyang People's Hospital, Tianfu Road No.107, Rongcheng District, Jieyang, 522000, Guangdong, People's Republic of China.
出版信息
BMC Womens Health. 2022 Oct 11;22(1):418. doi: 10.1186/s12905-022-02000-9.
BACKGROUND
The rupture of the corpus luteum (CL) may occur at all stages of a woman's reproductive life. Bleeding of the ruptured CL varies from self-limiting hemorrhage to massive hemoperitoneum, causing the shock and subsequent emergency surgery. But hemoperitoneum secondary to ruptured CL is a rare complication and situation for women with bleeding disorders.
CASE PRESENTATION
We here describe a case of severe CL hemorrhage with factor VIII deficiency. We chose conservative management instead of surgery for the abnormal hemostatic condition. With blood product and factor concentrate support, conservative management was successful in avoiding surgery in the episode of bleeding.
CONCLUSION
Gynecologist should be alert for the patients with abnormal hemostatic condition. Selective patients presenting with CL hemoperitoneum association with bleeding disorders may undergo conservative management and avoid the risk of surgery.
背景
黄体破裂可发生于女性生殖生命的各个阶段。破裂的黄体出血可从自限性出血到大量血性腹腔积血不等，导致休克和随后的紧急手术。但是，由于出血性疾病导致的黄体破裂后发生的血性腹腔积血是一种罕见的并发症和情况。
病例介绍
我们在此描述了一例因子 VIII 缺乏症导致的严重黄体出血病例。我们选择了保守治疗而不是手术，因为存在异常止血情况。通过血制品和因子浓缩物支持，保守治疗成功地避免了出血事件中的手术。
结论
妇科医生应警惕存在异常止血情况的患者。选择性地对伴有出血性疾病的黄体破裂腹腔积血患者进行保守治疗，可以避免手术的风险。
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