Ashizawa Reina, Rubio Natalie, Letcher Sophia, Parkinson Avery, Dmitruczyk Victoria, Kaplan David L
Department of Biology, Tufts University, Medford, MA 02155, USA.
Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Foods. 2022 Sep 30;11(19):3037. doi: 10.3390/foods11193037.
Cultured meat, or the practice of growing meat from cell culture, has been experiencing rapid advances in research and technology as the field of biotechnology attempts to answer the call to fight climate change and feed a growing global population. A major hurdle for cell-based meat products entering the market in the near-future is their price. The complex production facilities required to make such products will require advanced bioreactor systems, resources such as energy and water, and a skilled labor force, among other factors. The use of insect cells in this process is hypothesized to address some of these costs due to the characteristics that make them more resilient in cell culture when compared to traditional livestock-derived cells. To address the potential for cost savings by utilizing insect cells in the cultivation of protein-enriched foods, here we utilized a techno-economic assessment model. Three different insect cell lines were used in the model. The results indicate that insect cell lines offer potential to significantly reduce the cost per kilogram of cell cultivated meat, along with further opportunities to optimize production processes through technological advances and scaling.
培养肉,即通过细胞培养来生产肉类的做法,随着生物技术领域试图响应应对气候变化和养活不断增长的全球人口的号召,在研究和技术方面取得了迅速进展。基于细胞的肉类产品在不久的将来进入市场的一个主要障碍是其价格。生产此类产品所需的复杂生产设施将需要先进的生物反应器系统、能源和水等资源以及熟练的劳动力等因素。在这个过程中使用昆虫细胞被假设可以解决一些成本问题,因为与传统家畜来源的细胞相比,昆虫细胞在细胞培养中更具弹性。为了评估利用昆虫细胞培养富含蛋白质的食物可能节省成本的情况,我们在此使用了一种技术经济评估模型。该模型使用了三种不同的昆虫细胞系。结果表明,昆虫细胞系有潜力显著降低每千克细胞培养肉的成本,同时还有通过技术进步和扩大规模进一步优化生产过程的机会。