Renkler Nergis Zeynep, Cruz-Maya Iriczalli, Bonadies Irene, Guarino Vincenzo
Institute of Polymers, Composites and Biomaterials, National research Council of Italy, Mostra d'Oltremare Pad.20, V. le J.F. Kennedy 54, 80125 Naples, Italy.
Polymers (Basel). 2022 Oct 10;14(19):4249. doi: 10.3390/polym14194249.
In the last two decades, several processes have been explored for the development of micro and/or nanostructured substrates by sagely physically and/or chemically manipulating polymer materials. These processes have to be designed to overcome some of the limitations of the traditional ones in terms of feasibility, reproducibility, and sustainability. Herein, the primary aim of this work is to focus on the enormous potential of using a high voltage electric field to manipulate polymers from synthetic and/or natural sources for the fabrication of different devices based on elementary units, i.e., fibers or particles, with different characteristic sizes-from micro to nanoscale. Firstly, basic principles and working mechanisms will be introduced in order to correlate the effect of selected process parameters (i.e., an applied voltage) on the dimensional features of the structures. Secondly, a comprehensive overview of the recent trends and potential uses of these processes will be proposed for different biomedical and bio-sustainable application areas.
在过去二十年中,人们探索了多种方法,通过巧妙地对聚合物材料进行物理和/或化学处理来制备微结构和/或纳米结构基底。这些方法的设计必须克服传统方法在可行性、可重复性和可持续性方面的一些局限性。本文的主要目的是聚焦于利用高压电场来操控合成和/或天然来源的聚合物,以制造基于基本单元(即具有不同特征尺寸——从微米到纳米级的纤维或颗粒)的不同器件的巨大潜力。首先,将介绍基本原理和工作机制,以便关联所选工艺参数(即施加电压)对结构尺寸特征的影响。其次,将针对不同的生物医学和生物可持续应用领域,对这些方法的最新趋势和潜在用途进行全面概述。