Štulík Jan, Geri Gábor, Barna Michal, Klézl Zdeněk
Department of Spinal Surgery, First Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
Brain Spine. 2022 Jan 29;2:100871. doi: 10.1016/j.bas.2022.100871. eCollection 2022.
Surgical treatment of high-grade developmental spondylolisthesis remains controversial with paucity of data reporting complete reduction of the deformity, especially in pediatric patients.
To assess efficacy and safety of complete reduction and circumferential L5-S1 fusion in children with high-grade high-dysplastic spondylolisthesis. Emphasis was placed on fusion rates, correction of lumbosacral deformity and long-term clinical outcomes by means of patient-reported outcome measures (PROMs).
Consecutive series of 18 pediatric patients referred to surgery over an 11-years period. Several radiographic variables and PROMs were collected pre- and post-surgery with minimum follow-up of 2-years.
The mean age of cohort was 12.9 years with a mean follow-up of 7.8 years. Postoperatively, the mean slip was reduced from 64.4±9.8% to 4.5±5.9% with no loss of correction during follow-up. PROMs significantly improved following the index procedure (p<0.0001). Lumbo-pelvic parameters improved after surgery, including SS, but not PT. Development of adjacent level spondylolisthesis was noted in eight subjects (44%), two of these patients required additional surgery. Posterolateral and anterior fusion was obtained in 100% and 78% of cases, respectively. One patient developed a transient right-sided L5 nerve paresis after surgery that gradually resolved within one year post-surgery. Preoperatively, we recorded three patients with L5 nerve root motor deficit, which resolved completely in two cases and in one patient remained unchanged.
Complete reduction can safely be accomplished without an increased risk of nerve root injury. Coupled with single-level circumferential fusion, it provides high fusion rates with satisfactory spino-pelvic alignment.
对于重度发育性腰椎滑脱的手术治疗仍存在争议,缺乏关于畸形完全矫正的数据报道,尤其是在儿科患者中。
评估重度发育不良性腰椎滑脱患儿进行畸形完全矫正及L5 - S1全周融合的疗效和安全性。重点关注融合率、腰骶部畸形的矫正以及通过患者报告结局量表(PROMs)得出的长期临床结局。
连续纳入11年间接受手术治疗的18例儿科患者。术前和术后收集了多个影像学变量及PROMs,最短随访时间为2年。
队列的平均年龄为12.9岁,平均随访时间为7.8年。术后,平均滑脱率从64.4±9.8%降至4.5±5.9%,随访期间无矫正丢失。接受手术治疗后,PROMs显著改善(p<0.0001)。术后腰骶骨盆参数有所改善,包括矢状面垂直轴(SS),但骨盆倾斜角(PT)未改善。8例患者(44%)出现相邻节段腰椎滑脱,其中2例患者需要再次手术。分别有100%和78%的病例实现了后外侧融合和前路融合。1例患者术后出现短暂性右侧L5神经麻痹,术后1年内逐渐缓解。术前,我们记录了3例L5神经根运动功能障碍患者,其中2例完全恢复,1例保持不变。
畸形完全矫正可安全完成,且不会增加神经根损伤风险。结合单节段全周融合,可实现高融合率,并获得满意的脊柱骨盆对线。