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Context-dependent regulation of ferroptosis sensitivity.

作者信息

Magtanong Leslie, Mueller Grace D, Williams Kevin J, Billmann Maximilian, Chan Katherine, Armenta David A, Pope Lauren E, Moffat Jason, Boone Charles, Myers Chad L, Olzmann James A, Bensinger Steven J, Dixon Scott J

出版信息

Cell Chem Biol. 2022 Oct 20;29(10):1568. doi: 10.1016/j.chembiol.2022.08.008.

DOI:10.1016/j.chembiol.2022.08.008

PMID:36270234

Abstract

摘要

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Context-dependent regulation of ferroptosis sensitivity.

Cell Chem Biol. 2022 Oct 20;29(10):1568. doi: 10.1016/j.chembiol.2022.08.008.

Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma.

Theranostics. 2021 Mar 24;11(12):5650-5674. doi: 10.7150/thno.55482. eCollection 2021.

Ferroptosis is a type of autophagy-dependent cell death.

Semin Cancer Biol. 2020 Nov;66:89-100. doi: 10.1016/j.semcancer.2019.03.002. Epub 2019 Mar 14.

The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway.

Int J Mol Sci. 2020 Nov 9;21(21):8387. doi: 10.3390/ijms21218387.

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Biochem Soc Trans. 2020 Oct 30;48(5):2253-2259. doi: 10.1042/BST20200523.

Ferroptosis in plants: regulation of lipid peroxidation and redox status.

Biochem J. 2022 Apr 14;479(7):857-866. doi: 10.1042/BCJ20210682.

Metabolic regulation of ferroptosis in the tumor microenvironment.

J Biol Chem. 2022 Mar;298(3):101617. doi: 10.1016/j.jbc.2022.101617. Epub 2022 Jan 21.

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Front Cell Dev Biol. 2021 Jun 14;9:698679. doi: 10.3389/fcell.2021.698679. eCollection 2021.

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Cell Rep. 2019 Feb 5;26(6):1544-1556.e8. doi: 10.1016/j.celrep.2019.01.043.

Iron Metabolism in Ferroptosis.

Front Cell Dev Biol. 2020 Oct 7;8:590226. doi: 10.3389/fcell.2020.590226. eCollection 2020.

引用本文的文献

Hypoxia induced lipid droplet accumulation promotes resistance to ferroptosis in prostate cancer.

Oncotarget. 2025 Jun 25;16:532-544. doi: 10.18632/oncotarget.28750.

SCD1 Inhibition Blocks the AKT-NRF2-SLC7A11 Pathway to Induce Lipid Metabolism Remodeling and Ferroptosis Priming in Lung Adenocarcinoma.

Cancer Res. 2025 Jul 2;85(13):2485-2503. doi: 10.1158/0008-5472.CAN-24-2745.

Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.

Cell Chem Biol. 2025 Mar 20;32(3):408-422.e6. doi: 10.1016/j.chembiol.2024.09.008. Epub 2024 Oct 22.

Mechanisms and therapeutic potential of disulphidptosis in cancer.

Cell Prolif. 2025 Jan;58(1):e13752. doi: 10.1111/cpr.13752. Epub 2024 Oct 1.

Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking.

bioRxiv. 2024 May 9:2024.05.06.592780. doi: 10.1101/2024.05.06.592780.

Ironing out the role of ferroptosis in immunity.

Immunity. 2024 May 14;57(5):941-956. doi: 10.1016/j.immuni.2024.03.019.

Naringenin alleviates liver ﬁbrosis by triggering autophagy-dependent ferroptosis in hepatic stellate cells.

Heliyon. 2024 Mar 29;10(7):e28865. doi: 10.1016/j.heliyon.2024.e28865. eCollection 2024 Apr 15.

Ferroptosis and its current progress in gastric cancer.

Front Cell Dev Biol. 2024 Feb 28;12:1289335. doi: 10.3389/fcell.2024.1289335. eCollection 2024.

Selenium reduction of ubiquinone via SQOR suppresses ferroptosis.

Nat Metab. 2024 Feb;6(2):343-358. doi: 10.1038/s42255-024-00974-4. Epub 2024 Feb 13.

Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology.

Mol Oncol. 2024 Mar;18(3):479-516. doi: 10.1002/1878-0261.13582. Epub 2024 Jan 18.

Context-dependent regulation of ferroptosis sensitivity.

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