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低出生体重的种族差异。趋势与风险因素。

Racial differences in low birth weight. Trends and risk factors.

作者信息

Kleinman J C, Kessel S S

出版信息

N Engl J Med. 1987 Sep 17;317(12):749-53. doi: 10.1056/NEJM198709173171207.

Abstract

To identify the risk factors responsible for differences in birth weight between blacks and whites, we investigated the effects of four maternal characteristics (age, parity, marital status, and education) on rates of very low birth weight (less than 1500 g) and moderately low birth weight (between 1500 and 2500 g). Using 1983 national data, we found that the black:white rate ratio was 3.0 for very low birth weight and 2.3 for moderately low birth weight. The four maternal factors had directionally similar but quantitatively different effects on very low and moderately low birth weight among blacks and whites. Furthermore, the racial differences in infants' birth weights were greater among low-risk than among high-risk mothers, especially for very low birth weight (black:white ratios of 3.4 and 1.7, respectively). We also examined secular trends in the rates of low birth weight among blacks and whites. Between 1973 and 1983, births of infants with moderately low birth weights decreased more among whites than among blacks, whereas births of infants with very low birth weights increased among blacks and decreased among whites. Fifteen percent of the decline in the rate of moderately low birth weight among whites could be attributed to favorable changes in maternal characteristics (primarily an increase in educational level). Among blacks, adverse changes in maternal characteristics (primarily an increase in births to unmarried women) accounted for 35 percent of the increase in the rate of very low birth weight. The adverse effects of childbearing by teenagers on the outcome of pregnancy among blacks appear to have been overemphasized. The persistence of large racial differences in birth weight, even among mothers at low risk, emphasizes the need for specific targeted interventions to achieve further improvements in infant health.

摘要

为了确定导致黑人和白人出生体重差异的风险因素,我们研究了四个母亲特征(年龄、胎次、婚姻状况和教育程度)对极低出生体重(低于1500克)和中度低出生体重(1500至2500克之间)发生率的影响。利用1983年的全国数据,我们发现,极低出生体重的黑人与白人发生率之比为3.0,中度低出生体重为2.3。这四个母亲因素对黑人和白人的极低出生体重和中度低出生体重产生的影响在方向上相似,但在数量上不同。此外,低风险母亲中婴儿出生体重的种族差异比高风险母亲中更大,尤其是极低出生体重(黑人与白人之比分别为3.4和1.7)。我们还研究了黑人和白人低出生体重发生率的长期趋势。1973年至1983年期间,中度低出生体重婴儿的出生在白人中下降幅度大于黑人,而极低出生体重婴儿的出生在黑人中增加,在白人中减少。白人中度低出生体重发生率下降的15%可归因于母亲特征的有利变化(主要是教育水平的提高)。在黑人中,母亲特征的不利变化(主要是未婚妇女生育增加)占极低出生体重发生率上升的35%。青少年生育对黑人妊娠结局的不利影响似乎被过度强调了。出生体重方面巨大的种族差异持续存在,即使在低风险母亲中也是如此,这凸显了采取针对性具体干预措施以进一步改善婴儿健康状况的必要性。

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