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发展中国家人类免疫缺陷病毒感染患者白内障手术的结果。

Outcomes of cataract surgery in patients with Human Immunodeficiency Virus infection in a developing country.

机构信息

Department of Intraocular Lens and Cataract Services, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, India.

Department of Intraocular Lens and Cataract Services, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Coimbatore, India.

出版信息

Int Ophthalmol. 2023 May;43(5):1601-1609. doi: 10.1007/s10792-022-02559-0. Epub 2022 Oct 23.

Abstract

PURPOSE

To report the outcomes of cataract surgery in patients with Human Immunodeficiency Virus (HIV) infection. Setting Tertiary care ophthalmic hospital DESIGN: Retrospective study METHODS: This study included all eyes of patients with known HIV infection undergoing cataract surgery with a minimum follow-up of 6 months between January 2017 and December 2020. Patients who underwent combined surgeries and pediatric patients were excluded from analysis. Data were retrieved from electronic medical records and we documented demographics, history, detailed anterior and posterior segment examination, pre-operative grade and type of cataract, type of surgery done, its complication and post-operative course. All these parameters were recorded at the baseline visit and at 1 month and 6 months postoperatively.

RESULTS

One hundred and twenty nine eyes of 107 HIV infected patients that underwent cataract surgery were evaluated. Mature cataract was seen in 31% of the eyes. Features of HIV related uveitis/retinitis were seen in 21 (16.2%) eyes. Phacoemulsification was performed in 44 (34.1%) eyes while manual small incision cataract surgery (MSICS) was done in 85 (65.9%) eyes. Intra-operative complications were encountered in 4 (3.1%) eyes. At the final follow-up, there was a significant improvement in median corrected distance visual acuity (CDVA) from LogMAR 1.08 (5/60) at baseline to LogMAR 0 (6/6) at 6 months follow-up.

CONCLUSION

Patients with HIV infection usually present early and with advanced cataracts. Visual outcomes after cataract surgery are generally good but affected by presence of prior HIV related uveitis or retinitis.

摘要

目的

报告人类免疫缺陷病毒(HIV)感染患者白内障手术的结果。

背景

三级眼科医院。

设计

回顾性研究。

方法

本研究纳入了 2017 年 1 月至 2020 年 12 月期间所有接受白内障手术且已知 HIV 感染的患者的眼。排除接受联合手术和儿科患者的眼。从电子病历中检索数据,记录人口统计学、病史、详细的眼前段和眼后段检查、术前白内障分级和类型、手术类型、其并发症和术后过程。所有这些参数均在基线访视以及术后 1 个月和 6 个月时记录。

结果

共评估了 107 例 HIV 感染患者的 129 只眼。31%的眼为成熟白内障。21 只眼(16.2%)可见与 HIV 相关的葡萄膜炎/视网膜炎特征。44 只眼行超声乳化白内障吸除术(Phaco),85 只眼行手动小切口白内障囊外摘除术(MSICS)。术中并发症发生于 4 只眼(3.1%)。最终随访时,中位数矫正视力(CDVA)从基线时的 LogMAR 1.08(5/60)显著改善至 6 个月时的 LogMAR 0(6/6)。

结论

HIV 感染患者通常较早出现且白内障已处于晚期。白内障手术后的视力结果通常较好,但受先前 HIV 相关葡萄膜炎或视网膜炎的影响。

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