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静脉性卒中——一种不应被忽视的卒中亚型。

Venous stroke-a stroke subtype that should not be ignored.

作者信息

Zhou Yifan, Jiang Huimin, Wei Huimin, Liu Lu, Zhou Chen, Ji Xunming

机构信息

Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.

School of Engineering Medicine, Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University, Beijing, China.

出版信息

Front Neurol. 2022 Oct 6;13:1019671. doi: 10.3389/fneur.2022.1019671. eCollection 2022.

Abstract

Based on the etiology, stroke can be classified into ischemic or hemorrhagic subtypes, which ranks second among the leading causes of death. Stroke is caused not only by arterial thrombosis but also by cerebral venous thrombosis. Arterial stroke is currently the main subtype of stroke, and research on this type has gradually improved. Venous thrombosis, the particular type, accounts for 0.5-1% of all strokes. Due to the lack of a full understanding of venous thrombosis, as well as its diverse clinical manifestations and neuroimaging features, there are often delays in admission for it, and it is easy to misdiagnose. The purpose of this study was to review the pathophysiology mechanisms and clinical features of arterial and venous thrombosis and to provide guidance for further research on the pathophysiological mechanism, clinical diagnosis, and treatment of venous thrombosis. This review summarizes the pathophysiological mechanisms, etiology, epidemiology, symptomatology, diagnosis, and treatment heterogeneity of venous thrombosis and compares it with arterial stroke. The aim is to provide a reference for a comprehensive understanding of venous thrombosis and a scientific understanding of various pathophysiological mechanisms and clinical features related to venous thrombosis, which will contribute to understanding the pathogenesis of intravenous stroke and provide insight into diagnosis, treatment, and prevention.

摘要

根据病因,中风可分为缺血性或出血性亚型,在主要死因中排名第二。中风不仅由动脉血栓形成引起,也由脑静脉血栓形成引起。动脉性中风是目前中风的主要亚型,对此类型的研究已逐渐完善。静脉血栓形成这种特殊类型占所有中风的0.5 - 1%。由于对静脉血栓形成缺乏全面了解,以及其临床表现和神经影像学特征多样,其入院往往延迟,且容易误诊。本研究的目的是回顾动脉和静脉血栓形成的病理生理机制及临床特征,为进一步研究静脉血栓形成的病理生理机制、临床诊断和治疗提供指导。本综述总结了静脉血栓形成的病理生理机制、病因、流行病学、症状学、诊断及治疗异质性,并将其与动脉性中风进行比较。目的是为全面了解静脉血栓形成以及科学认识与静脉血栓形成相关的各种病理生理机制和临床特征提供参考,这将有助于理解静脉性中风的发病机制,并为诊断、治疗和预防提供见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45eb/9582250/acd09b387da1/fneur-13-1019671-g0001.jpg

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