Ogawa Haruna, Komatsu Shuhei, Matsubara Daiki, Hamada Satoshi, Nishiko Mizuki, Konishi Tomoki, Soga Koji, Ikeda Jun, Shimomura Katsumi, Taniguchi Fumihiro, Shioaki Yasuhiro
Dept. of Surgery, Japanese Red Cross Kyoto Daiichi Hospital.
Gan To Kagaku Ryoho. 2022 Oct;49(10):1163-1165.
Recurrent gastric cancer(GC)with splenic metastasis showed poor prognosis, and its treatment strategy remains unclear. Recently, studies identified the considerable prognostic effect of metastasectomy in GC following intensive chemotherapy. Here, we successfully treated a patient with Epstein-Barr virus-positive esophagogastric junctional cancer with splenic metastasis who underwent metastasectomy and obtained pathological complete response following immune checkpoint therapy and had long-term survival. We reviewed the literature to discuss the clinical significance of our treatment strategy.
伴有脾脏转移的复发性胃癌预后较差,其治疗策略仍不明确。最近,研究发现了在强化化疗后进行转移灶切除术对胃癌预后的显著影响。在此,我们成功治疗了一名患有脾脏转移的爱泼斯坦-巴尔病毒阳性食管胃交界癌患者,该患者接受了转移灶切除术,并在免疫检查点治疗后获得了病理完全缓解,且长期存活。我们回顾文献以讨论我们治疗策略的临床意义。