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比较蜂蜜与止咳药物对儿科患者的疗效:一项系统评价

Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review.

作者信息

Mashat Ghadi D, Hazique Mohammad, Khan Kokab Irfan, Ramesh Prasana, Kanagalingam Suthasenthuran, Ul Haq Zargham, Victory Srinivasan Nishok, Khan Aujala Irfan, Khan Safeera

机构信息

Pediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

出版信息

Cureus. 2022 Sep 20;14(9):e29346. doi: 10.7759/cureus.29346. eCollection 2022 Sep.

Abstract

Coughing is one of the most prevalent symptoms in children presenting at outpatient departments. This systematic review aimed to review previous literature in order to compare the use of honey and antitussive medications for treating coughs in children. Literature was screened across five databases using Medical Subject Heading (MeSH) strategy, keywords, and inclusion and exclusion criteria. The remaining literature was evaluated using a quality appraisal tool checklist. This review includes systematic reviews, ‎‎meta-analyses, randomized controlled trials (RCTs), observational studies, cross-sectional studies, and articles ‎without ‎a defined ‎methodology section. This review suggests that honey is effective in treating children above 12 months of age, while cold and cough medications (CCMs) are safe if administered at therapeutic doses. Since fatalities can occur in children under two years of age, further RCT studies on CCMs are required to establish safety across all age groups.

摘要

咳嗽是儿科门诊最常见的症状之一。本系统评价旨在回顾以往文献,以比较蜂蜜和镇咳药物治疗儿童咳嗽的效果。采用医学主题词(MeSH)策略、关键词以及纳入和排除标准,对五个数据库中的文献进行筛选。使用质量评估工具清单对剩余文献进行评估。本评价纳入了系统评价、荟萃分析、随机对照试验(RCT)、观察性研究、横断面研究以及未明确方法学部分的文章。本评价表明,蜂蜜对12个月以上儿童的咳嗽治疗有效,而感冒咳嗽药(CCM)在治疗剂量下使用是安全的。由于两岁以下儿童可能发生死亡,因此需要进一步开展关于CCM的随机对照试验研究,以确定其在所有年龄组中的安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e68e/9583571/0eebc54add7a/cureus-0014-00000029346-i01.jpg

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