Shin Soonsu, Choi Jun-Hyeok, Lee Kyung-Eun, Yoon Jin-Ha, Lee Wanhyung
Department of Preventive Medicine, Graduate School, Kyung Hee University, Seoul 02447, Korea.
Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, Ulsan 44429, Korea.
Cancers (Basel). 2022 Oct 21;14(20):5164. doi: 10.3390/cancers14205164.
To compare the risk of developing gastrointestinal (GI) cancer according to industrial groups, we performed a retrospective cohort study using the database of the Korea National Health Insurance Service (NHIS). We calculated the age-standardized incidence ratios (SIRs) and 95% confidence intervals (95% CIs) for the types of GI cancers according to the Korean Standard Industrial Classification (KSIC) compared with the whole employee population. The highest SIR for all GI cancer was found in the "Mining and quarrying" section (SIR, 1.30; 95% CI, 1.14-1.47), followed by the "Transportation and storage" section (SIR, 1.27; 95% CI, 1.24-1.30). Miners and quarriers had the highest risk of developing gastric cancer (SIR, 1.29; 95% CI, 1.06-1.55) and cancer of the liver and intrahepatic bile ducts (SIR, 1.48; 95% CI, 1.17-1.86). Transportation workers had the highest SIR of cancer of the lip, oral cavity, and pharynx (SIR, 1.27; 95% CI, 1.13-1.43) and cancers of the rectum, anus, and anal canal (SIR, 1.27; 95% CI, 1.19-1.35). There were distinct GI cancers with an elevated risk in each industry group. Our findings imply that distinct cancer prevention programs should be developed for each industrial sector.
为了根据产业类别比较发生胃肠道(GI)癌症的风险,我们利用韩国国民健康保险服务(NHIS)的数据库进行了一项回顾性队列研究。我们根据韩国标准产业分类(KSIC)计算了与全体员工人群相比的胃肠道癌症类型的年龄标准化发病率(SIR)和95%置信区间(95%CI)。所有胃肠道癌症中最高的SIR出现在“采矿和采石”部门(SIR,1.30;95%CI,1.14 - 1.47),其次是“运输和仓储”部门(SIR,1.27;95%CI,1.24 - 1.30)。矿工和采石工人患胃癌(SIR,1.29;95%CI,1.06 - 1.55)以及肝癌和肝内胆管癌(SIR,1.48;95%CI,1.17 - 1.86)的风险最高。运输工人患唇、口腔和咽癌(SIR,1.27;95%CI,1.13 - 1.43)以及直肠癌、肛门和肛管癌(SIR,1.27;95%CI,1.19 - 1.35)的SIR最高。每个行业组中都有不同的胃肠道癌症风险升高。我们的研究结果表明,应为每个工业部门制定不同的癌症预防计划。