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新型冠状病毒肺炎合并肺栓塞患者的床旁超声心动图特征

Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism.

作者信息

Klasnja Slobodan, Manojlovic Andrea, Popadic Viseslav, Ivankovic Tatjana, Ninkovic Nebojsa, Rajovic Nina, Popovic Maja, Nikolic Novica, Brajkovic Milica, Radojevic Aleksandra, Lasica Ratko, Rajsic Sasa, Todorovic Zoran, Brankovic Marija, Radonjic Tijana, Memon Lidija, Mrda Davor, Milic Natasa, Zdravkovic Marija

机构信息

University Hospital Medical Center Bežanijska kosa, 11000 Belgrade, Serbia.

Institute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.

出版信息

Diagnostics (Basel). 2022 Sep 30;12(10):2380. doi: 10.3390/diagnostics12102380.

Abstract

INTRODUCTION

Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications.

METHODS

An observational study was conducted on 32 consecutive patients with confirmed pulmonary embolism and COVID-19 infection treated in the Intensive Care Unit of the University Hospital Medical Center "Bežanijska kosa", Belgrade, Serbia, between April 2021 and March 2022. Predictors of the need for oxygen support were determined, while point-of-care echocardiographic parameters and various anamnestic, laboratory, and clinically significant parameters were correlated with the Pulmonary Embolism Severity Index (PESI) score.

RESULTS

More than two-thirds of patients in our study had PE symptoms present at hospital admission (68.8%). The majority of patients had segmental pulmonary embolism (48.4%), with high to very high PESI score values in 31.3% of patients. Pneumonia was present in 68.8% of the study population. The PESI score was negatively correlated with diastolic blood pressure and SaO2 at the time of PE diagnosis, LV ejection fraction, and PVAT. A positive correlation was found between the PESI score, maximum CRP, and D-dimer at the time of PTE diagnosis. A larger right ventricular diameter was associated with a greater need for oxygen support.

CONCLUSION

Point-of-care echocardiography is a valuable tool for the risk assessment of COVID-19 patients with pulmonary embolism. Right ventricular size stood out as a significant marker of disease severity.

摘要

引言

血栓形成并发症,如肺栓塞,在新冠肺炎患者中很常见。即时超声检查是疑似或确诊并发症的危重症患者进行病情判断的高度推荐工具。

方法

对2021年4月至2022年3月期间在塞尔维亚贝尔格莱德“贝扎尼什卡科萨”大学医院医疗中心重症监护病房接受治疗的32例确诊肺栓塞且感染新冠肺炎的连续患者进行了一项观察性研究。确定了氧气支持需求的预测因素,同时将即时超声心动图参数以及各种既往史、实验室和临床重要参数与肺栓塞严重程度指数(PESI)评分相关联。

结果

在我们的研究中,超过三分之二的患者在入院时出现肺栓塞症状(68.8%)。大多数患者患有节段性肺栓塞(48.4%),31.3%的患者PESI评分值高到非常高。68.8%的研究人群患有肺炎。PESI评分与肺栓塞诊断时的舒张压和血氧饱和度、左心室射血分数以及肺静脉心房时间差呈负相关。在肺血栓栓塞症诊断时,PESI评分与最大C反应蛋白和D - 二聚体之间存在正相关。右心室直径越大,氧气支持需求越大。

结论

即时超声心动图是评估新冠肺炎合并肺栓塞患者风险的有价值工具。右心室大小是疾病严重程度的重要标志。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d21/9600333/384305133de8/diagnostics-12-02380-g001.jpg

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