0至36个月婴儿眼压的变化及其与角膜直径的相关性。

Changes to intraocular pressure and its correlation with corneal diameter in infants aged from 0 to 36 months.

作者信息

Wang Jian-Cang, Du Fei-Fan, Meng Shuo-Shuo, Wei Yun-Shuo, Guo Xi-Ting

机构信息

Department of Ophthalmology, Hebei Children's Hospital, Hebei Medical University, Shijiazhuang, China.

出版信息

Front Pediatr. 2022 Oct 10;10:954337. doi: 10.3389/fped.2022.954337. eCollection 2022.

DOI:10.3389/fped.2022.954337

PMID:36299698

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9589223/

Abstract

OBJECTIVE

This study examines the distribution and development of intraocular pressure (IOP) in infants aged from 0 to 36 months and analyzes its correlation with corneal diameter.

METHODS

The study used a retrospective case analysis methodology. Healthy infants treated in the ophthalmology department of Hebei Children's Hospital from December 2012 to December 2020 were included in the study. Among these infants, 385 had their IOP measured, and 432 had their corneal diameters measured. Furthermore, information such as birth history, growth and development, IOP, and corneal diameter were collected. Their IOPs were measured with an iCare portable rebound tonometer when the child was awake and calm, and the corneal diameter was measured with a Castroviejo caliper under chloral hydrate sedation. The infants were divided into five groups according to age, and SPSS statistical software was used to analyze, compare, and correlate IOP and corneal diameter variations.

RESULTS

The mean IOP values of 0-1 month, 1-6 months, 6-12 months, 12-24 months and 24-36 months groups were 7.42 ± 1.92, 9.10 ± 2.85, 12.00 ± 3.15, 13.72 ± 3.09, and 15.14 ± 2.67 mmHg, respectively. The differences in IOP of the 0-1 month old infants and the 1-6 months old infants with the other three groups were statistically significant; the difference in IOP between the 6-12 months group and the 24-36 months group was statistically significant. In the studied groups, the horizontal corneal diameters were 9.78 ± 0.14, 10.50 ± 0.29, 10.86 ± 0.23, 11.38 ± 0.07, and 11.72 ± 0.04 mm, respectively, and the vertical diameters of the cornea were 9.28 ± 0.26, 10.07 ± 0.18, 10.28 ± 0.14, 10.56 ± 0.24, and 10.85 ± 0.03 mm, respectively. The differences in the vertical and horizontal diameters of the cornea among the groups were statistically significant.

CONCLUSION

Infants' IOP and corneal diameter positively correlate with age, and they peak in the first 12 months.

摘要

目的

本研究探讨0至36个月婴儿眼压（IOP）的分布及发育情况，并分析其与角膜直径的相关性。

方法

本研究采用回顾性病例分析方法。纳入2012年12月至2020年12月在河北儿童医院眼科接受治疗的健康婴儿。其中，385例测量了眼压，432例测量了角膜直径。此外，收集了出生史、生长发育、眼压和角膜直径等信息。在患儿清醒平静时用iCare便携式回弹眼压计测量眼压，在水合氯醛镇静下用Castroviejo卡尺测量角膜直径。根据年龄将婴儿分为五组，使用SPSS统计软件分析、比较眼压和角膜直径的变化并进行相关性分析。

结果

0至1个月、1至6个月、6至12个月、12至24个月和及24至36个月组的平均眼压值分别为7.42±1.92、9.10±2.85、12.00±3.15、13.72±3.09和15.14±2.67 mmHg。0至1个月和1至6个月婴儿的眼压与其他三组相比差异有统计学意义；6至12个月组和24至36个月组的眼压差异有统计学意义。在研究组中，角膜水平直径分别为9.78±0.14、10.50±0.29、10.86±0.23、11.38±0.07和11.72±0.04 mm，角膜垂直直径分别为9.28±0.26、10.07±0.18、10.28±0.14、10.56±0.24和10.85±0.03 mm。各组角膜垂直和水平直径差异有统计学意义。