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胎盘植入谱系疾病:一项为期 2 年的回顾性观察研究。

Placenta Accreta Spectrum: A 2-year Retrospective Observational Study.

机构信息

Department of Anaesthesiology and Critical Care Medicine, University Hospital Galway.

出版信息

Ir Med J. 2022 Aug 18;115(7):629.

Abstract

Aims To assess the management and outcomes of Placenta Accreta Spectrum disorders and highlight the important management recommendations from international guidelines. Methods A retrospective audit of women diagnosed with Placenta Accreta Spectrum disorder from January 2018 to December 2019. Results Nine cases (0.16%) of placenta accreta from 5695 births were identified. All women received caesarean section under general anaesthesia. Caesarean hysterectomy occurred in seven cases (78%). Mean (±SD) age of women was (34.4 ± 3.9 years) and mean parity score was (3.2 ± 1.2). Mean gestational age at birth was 35.1 ± 0.8 weeks. Bilateral iliac artery balloon occlusion occurred in eight (89%) cases. Median estimated blood loss [range] was 1700 mL [1000-7000] with only 11% of patients (1/9) experiencing more than 3L of blood loss. Intraoperative red blood cell transfusion occurred in six cases (67%). Median number of units of red cell transfusion [range] was four units [0-10]. Mean hospital length of stay was (6.7 ± 1.1 days) and there were no maternal deaths. Multidisciplinary team involvement of senior anaesthetists and obstetricians was noted in all cases. Discussion Placenta accreta spectrum is increasing in incidence in obstetric practice and is associated with significant maternal morbidity and mortality. Implementing national guidelines can improve patient outcomes.

摘要

目的 评估胎盘植入谱系疾病的管理和结局,并强调国际指南中的重要管理建议。

方法 对 2018 年 1 月至 2019 年 12 月期间被诊断为胎盘植入谱系疾病的妇女进行回顾性审计。

结果 在 5695 例分娩中,发现 9 例(0.16%)胎盘植入。所有妇女均在全身麻醉下接受剖宫产术。7 例(78%)行剖宫产子宫切除术。妇女的平均(±SD)年龄为(34.4 ± 3.9 岁),平均产次评分为(3.2 ± 1.2)。出生时的平均(±SD)孕周为 35.1 ± 0.8 周。双侧髂动脉球囊闭塞发生在 8 例(89%)中。中位估计出血量[范围]为 1700 毫升[1000-7000],只有 11%的患者(1/9)出血量超过 3 升。术中输注红细胞 6 例(67%)。中位红细胞输注单位数[范围]为 4 单位[0-10]。平均住院时间为(6.7 ± 1.1)天,无产妇死亡。所有病例均有高级麻醉师和产科医生的多学科团队参与。

讨论 胎盘植入谱系疾病在产科实践中的发病率不断增加,与产妇发病率和死亡率显著相关。实施国家指南可以改善患者的结局。

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