Department of Community Nutrition, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Community Nutrition, School of Nutrition and Food Science, Shiraz University of Medical Sciences, Shiraz, Iran.
Sci Rep. 2022 Nov 1;12(1):18365. doi: 10.1038/s41598-022-22827-4.
There was a lack of evidence on the association between dairy intake and metabolic health status in overweight/obese adolescents. This study evaluated the association between dairy intake and metabolic health status in overweight/obese Iranian adolescents. Overweight/obese adolescents (n = 203; 101 boys and 102 girls) selected by a multistage cluster random sampling method have participated in this cross-sectional study. Dietary intake was assessed using a validated 147-item food frequency questionnaire. Anthropometric indices, blood pressure, fasting glucose, insulin, and lipid profile were measured. Participants were categorized to metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO) according to International Diabetes Federation (IDF) criteria and a combination of IDF with Homeostasis Model Assessment Insulin Resistance (HOMA-IR) criteria. The frequency of MUO based on IDF, and IDF/HOMA-IR definitions was 38.9% and 33.0%, respectively. In fully-adjusted model, participants in the highest tertile of dairy intake had 61% lower odds of MUO based on IDF criteria (OR = 0.39, 95% CI 0.15-0.99). Higher dairy intake was associated with a non-significant lower risk of MUO according to IDF/HOMA-IR definition in the maximally-adjusted model (OR = 0.44, 95% CI 0.17-1.16). Stratifies analysis by sex and body mass index revealed that the association was stronger in girls and overweight subjects. Furthermore, higher intake of low-fat dairy was related to a reduced likelihood of MUO, while higher intake of high-fat dairy was related to increased odds of MUO. This community-based cross-sectional study revealed that higher intake of dairy was associated with a significant lower odd of MUO among Iranian adolescents, especially in girls and overweight subjects.
超重/肥胖青少年的乳制品摄入量与代谢健康状况之间的关联缺乏证据。本研究评估了超重/肥胖伊朗青少年乳制品摄入量与代谢健康状况之间的关系。采用多阶段聚类随机抽样方法选择了 203 名超重/肥胖青少年(101 名男孩和 102 名女孩)参与这项横断面研究。使用经过验证的 147 项食物频率问卷评估饮食摄入。测量了人体测量指数、血压、空腹血糖、胰岛素和血脂谱。根据国际糖尿病联合会(IDF)标准和 IDF 与稳态模型评估胰岛素抵抗(HOMA-IR)标准的组合,将参与者分为代谢健康肥胖(MHO)和代谢不健康肥胖(MUO)。根据 IDF 和 IDF/HOMA-IR 定义,MUO 的频率分别为 38.9%和 33.0%。在完全调整的模型中,乳制品摄入量最高三分位的参与者根据 IDF 标准发生 MUO 的可能性降低 61%(OR=0.39,95%CI 0.15-0.99)。在最大调整模型中,根据 IDF/HOMA-IR 定义,较高的乳制品摄入量与 MUO 的风险降低呈非显著相关(OR=0.44,95%CI 0.17-1.16)。按性别和体重指数进行分层分析显示,这种关联在女孩和超重人群中更强。此外,较高的低脂乳制品摄入量与 MUO 的可能性降低有关,而较高的高脂乳制品摄入量与 MUO 的可能性增加有关。这项基于社区的横断面研究表明,伊朗青少年中较高的乳制品摄入量与 MUO 的发生风险显著降低有关,尤其是在女孩和超重人群中。