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当前 HIV 感染者临床管理和关怀面临的挑战及应对策略:第 12 届国际艾滋病与老龄化研讨会的研究结果。

Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop.

机构信息

Department of Biostatistics and Data Science, University of Texas Medical Branch, Galveston, Texas, USA.

Department of Psychiatry, University of California San Diego, San Diego, California, USA.

出版信息

AIDS Res Hum Retroviruses. 2023 Jan;39(1):1-12. doi: 10.1089/AID.2022.0079. Epub 2022 Nov 23.

Abstract

People with HIV on combination antiretroviral therapy (ART) have longer life expectancy and are increasingly experiencing age-related comorbidities. Thus, aging with HIV has become a central issue in clinical care and research, which has been particularly challenging with the intersection of the ongoing coronavirus (COVID)-19 pandemic. Since 2009, the International Workshop on HIV and Aging has served as a multidisciplinary platform to share research findings from cross-disciplinary fields along with community advocates to address critical issues in HIV and aging. In this article, we summarize the key oral presentations from the 12th Annual International Workshop on HIV and Aging, held virtually on September 23rd and 24, 2021. The topics ranged from basic science research on biological mechanisms of aging to quality of life and delivery of care under the COVID-19 pandemic. This workshop enriched our understanding of HIV and aging under the COVID-19 pandemic, identified challenges and opportunities to combat the impact of COVID-19 on HIV communities, and also provided updated research and future directions of the field to move HIV and aging research forward, with the ultimate goal of successful aging for older people with HIV.

摘要

接受联合抗逆转录病毒疗法 (ART) 的艾滋病毒感染者的预期寿命更长,并且越来越多地出现与年龄相关的合并症。因此,艾滋病毒相关老龄化已成为临床护理和研究的核心问题,而持续的冠状病毒 (COVID)-19 大流行的交叉问题使得这一问题变得更加具有挑战性。自 2009 年以来,艾滋病毒与老龄化问题国际研讨会一直是一个多学科平台,用于分享跨学科领域的研究成果以及社区倡导者的意见,以解决艾滋病毒与老龄化问题中的关键问题。在本文中,我们总结了 2021 年 9 月 23 日和 24 日虚拟举行的第 12 届艾滋病毒与老龄化问题国际研讨会的主要口头报告。这些主题范围从衰老的生物学机制的基础科学研究到 COVID-19 大流行下的生活质量和护理提供。本次研讨会丰富了我们对 COVID-19 大流行下艾滋病毒与老龄化问题的理解,确定了应对 COVID-19 对艾滋病毒社区影响的挑战和机遇,并为该领域提供了最新的研究和未来方向,以推进艾滋病毒和老龄化研究,最终目标是让艾滋病毒感染者实现健康老龄化。

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