LIFE Child Leipzig Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany.
Leipzig University Hospital for Children and Adolescents, Leipzig University, Leipzig, Germany.
BMC Public Health. 2022 Nov 10;22(1):2058. doi: 10.1186/s12889-022-14377-1.
To investigate environmental and social risk factors for myopia in children and adolescents in Germany.
1437 children aged between 3 and 18 inclusive were examined as part of the LIFE Child study based in Leipzig, Germany. Information about leisure time activities and social status was ascertained by parents and children in a questionnaire. Refractive status was attained by measuring noncycloplegic autorefraction. Myopia was defined as spherical equivalent (SE) ≤ - 0.75 D. Risk factors were identified using multiple logistic regression analysis.
In multiple logistic regression analysis, myopia was significantly associated with less frequent outdoor activity ("once a week" vs. "twice a week or more": odds ratio (OR) 4.35, 95% confidence interval (CI) 1.89-9.98, p<0.01) and longer near work sessions (1-2 h vs. < 1 h: OR 1.83, CI 1.10-3.04, p=0.02; > 3 h vs. < 1 h: OR 3.71, CI 1.43-9.61, p<0.01) after adjustment for age, sex and socioeconomic status (SES). Duration of outdoor activity, near work frequency and SES showed no significant association with myopia (p > 0.05). Children with a lower SES were involved in longer periods of outdoor and near work activities but on fewer occasions over the course of the week, although this connection was not significant.
Myopia is associated with environmental factors. The present findings suggest that daily exposure to sunlight and a restriction of long-duration near work activities might protect against pathological eye growth. Prevention strategies should be implemented for children at all ages.
研究德国儿童和青少年近视的环境和社会风险因素。
在德国莱比锡的 LIFE Child 研究中,对 1437 名年龄在 3 至 18 岁之间的儿童进行了检查。家长和儿童通过问卷了解休闲活动和社会地位信息。通过测量非睫状肌自动折射来获得屈光状态。近视定义为球镜等效值(SE)≤-0.75 D。使用多元逻辑回归分析确定危险因素。
在多元逻辑回归分析中,近视与户外活动频率较低显著相关(“每周一次”与“每周两次或更多次”:优势比(OR)4.35,95%置信区间(CI)1.89-9.98,p<0.01)和近距离工作时间较长(1-2 小时与<1 小时:OR 1.83,CI 1.10-3.04,p=0.02;>3 小时与<1 小时:OR 3.71,CI 1.43-9.61,p<0.01),校正年龄、性别和社会经济地位(SES)后。户外活动时间、近距离工作频率和 SES 与近视无显著相关性(p>0.05)。SES 较低的儿童参与户外活动和近距离工作的时间较长,但每周参与的次数较少,尽管这种联系并不显著。
近视与环境因素有关。本研究结果表明,每天暴露在阳光下并限制长时间近距离工作活动可能有助于防止病理性眼轴增长。应在所有年龄段的儿童中实施预防策略。